VPBank Partners With CleverTap To Transform Vietnam’s Banking Experience

San Francisco, CA & Hanoi, Oct 17, 2024 - (ACN Newswire via SeaPRwire.com) - VPBank, one of Vietnam’s largest private banks, partners with CleverTap, the all-in-one customer engagement platform, to deepen understanding of customers and their aspirations and use the insights to deliver hyper-personalized experiences to users, at scale. VPBank aims to elevate customer experience and drive higher conversions on products and offers through highly targeted campaigns built on complex, real-time segmentation that quickly connects with customers. Through this association with CleverTap, VPBank’s objective is to improve engagement, deepen relationships and drive higher retention, while keeping costs low.Established in 1993, VPBank operates in a wide variety of businesses including retail banking, corporate banking, wealth management, and consumer finance. VPBank aims to become a top-ranking financial institution among joint stock commercial banks in Vietnam, in terms of business scale, market share, and service quality. Leveraging CleverTap’s AI/ML-powered capability suite, Clever.AI, VPBank will be able to hyper-personalize its engagement via multiple automation and journeys. It will enable a seamless and omnichannel onboarding experience for new users, driving higher success rates for key milestones such as registration and the first transaction. With the unified customer view on CleverTap, VPBank can identify high-intent users and target them with contextual and relevant offerings, achieving an increase in customer lifetime value.Varun Krishna, Head of Digital Marketing, VPBank said, “We’ve always strived to maintain our position as one of Vietnam’s leading financial institutions. In an increasingly competitive banking landscape, delivering personalized and meaningful customer experiences is paramount. Partnering with CleverTap empowers us to harness advanced AI-driven insights, enabling us to engage our customers more effectively and tailor our offerings to their unique needs across digital channels. This collaboration not only enhances our ability to connect with customers on a deeper level but also drives sustained growth and loyalty. Together, we are committed to setting new standards in customer engagement and positioning VPBank as the most trusted and preferred bank in Vietnam.”Mai Vo, Country Manager, CleverTap said, “Vietnam’s banking sector is at the precipice of a new era of growth. Our partnership with VPBank couldn’t be timed better. With a legacy of innovation and customer-centricity, VPBank has consistently set benchmarks in the Vietnamese banking industry. Their commitment to using technology for crafting exceptional customer experiences aligns perfectly with our vision. Together, with CleverTap’s state-of-the-art omnichannel platform, personalizing and enhancing customer engagement has never been more seamless. This partnership is not only a testament to CleverTap’s expertise in driving conversion and retention but also underscores VPBank’s leadership in propelling Vietnam's banking sector into a new era of excellence”About CleverTapCleverTap is the leading all-in-one customer engagement platform that helps brands unlock limitless customer lifetime value. CleverTap is trusted by over 2000 brands like Domino’s, Levis, Jio, Papa John’s, Zomato, Kotak Bank, Air Asia, Carousell, TD Bank, and Tesco to help build personalized experiences for all their customers. The platform is powered by TesseractDB™ – the world’s first purpose-built database for customer engagement, offering speed and cost efficiency at scale.Backed by top-tier investors such as Accel, Peak XV Partners, Tiger Global, CDPQ and 360 One, the company is headquartered in San Francisco, with presence across Seattle, London, São Paulo, Bogota, Mexico, Amsterdam, Sofia, Dubai, Mumbai, Bangalore, Singapore, Vietnam, and Jakarta.For more information, visit clevertap.com or follow us on:LinkedIn: https://www.linkedin.com/company/clevertap/  X: https://twitter.com/CleverTap  Forward-Looking StatementsSome of the statements in this press release may represent CleverTap's belief in connection with future events and may be forward-looking statements, or statements of future expectations based on currently available information. CleverTap cautions that such statements are naturally subject to risks and uncertainties that could result in the actual outcome being absolutely different from the results anticipated by the statements mentioned in the press release.Factors such as the development of general economic conditions affecting our business, future market conditions, our ability to maintain cost advantages, uncertainty with respect to earnings, corporate actions, client concentration, reduced demand, liability or damages in our service contracts, unusual catastrophic loss events, war, political instability, changes in government policies or laws, legal restrictions impacting our business, impact of pandemic, epidemic, any natural calamity and other factors that are naturally beyond our control, changes in the capital markets and other circumstances may cause the actual events or results to be materially different, from those anticipated by such statements. CleverTap does not make any representation or warranty, express or implied, as to the accuracy, completeness, or updated or revised status of such statements. Therefore, in no case whatsoever will CleverTap and its affiliate companies be liable to anyone for any decision made or action taken in conjunction.For more information:SONY SHETTYDirector, Communications, CleverTap+91 9820900036sony@clevertap.com  ASHMIT CHAUDHARYAssociate Consultant, Archetype+91 8850752121ashmit.chaudhary@archetype.co  Copyright 2024 ACN Newswire via SeaPRwire.com.

Athos Announces Positive Topline Phase 1 Data for its AI-Generated, Novel, Oral G9A Inhibitor ATH-063, Demonstrating Selective Expansion and Activation of Potent Anti-Inflammatory Regulatory T Cells

ATH-063 significantly increased the number of circulating regulatory T cells (Tregs) across all doses and demonstrated enrichment in six well-described genes related to induced Treg anti-inflammatory activitiesNo serious adverse effects or dose limiting toxicities were observed at any dose level, and ATH-063 demonstrated favorable pharmacokinetics (PK) The data provides clinical verification for Athos’ Proprietary AI2 (Artificial Intelligence for Autoimmune drug development) computational software platform which generated ATH-063LOS ANGELES, CA, Oct 17, 2024 - (ACN Newswire via SeaPRwire.com) - Athos Therapeutics, Inc. ("Athos"), a clinical stage biotechnology company pioneering the development of precision small molecule therapeutics for patients with immune-mediated diseases, today announced topline results for the company's Phase 1 clinical trial of ATH-063, an investigational oral small molecule G9A inhibitor and the company's lead asset in development for the treatment of inflammatory bowel disease (IBD).The clinical trial was a randomized, double-blind, placebo-controlled study in healthy volunteers designed to evaluate safety and PK as well as provide pharmacodynamic (PD) data to provide confirmation of ATH-063's proposed mechanism of action. The trial was conducted as sequential single ascending dose (SAD) (n=32) and multiple ascending dose (MAD) (n=32) arms, and a separate food-effect (FE) (n=12) arm. Four doses (25, 75, 150, and 250 mg) of ATH-063 were administered orally.PD data showed ATH-063 selective expansion and activation of Tregs, consistent with predictions made by Athos' AI2 platform:Statistically significant increases (p<0.001) in the number of blood Tregs were observed at all ATH-063 dose levels compared to placebo subjects, and demonstrated correlation between ATH-063 blood levels and number of TregsBlood ATH-063 concentration positively correlated with increase in multiple key biomarkers of Treg activity, including strong correlation with FOXP3 (p=0.003)Induced Tregs demonstrated enrichment of six well-described genes related to Treg anti-inflammatory activitiesSTAT5A, a key signaling molecule related to induced Tregs, was activated in all cohorts and doses (p=0.0003)PD data demonstrated correlation with key biomarkers of IBD disease activity, supporting further development of ATH-063 as a treatment for IBD:Blood ATH-063 concentration correlated (p=0.012)with reduction of OSM, a well-established biomarker related to TNFA resistanceBlood ATH-063 concentration correlated with reduction of calprotectin monomers, which is an established biomarker for IBDATH-063 was well tolerated across all dose groups: No serious adverse effect or dose limiting toxicities were observed at any dose levelRobust PK results and dose proportional increases in blood levels: ATH-063 showed favorable PK results with dose-proportional increases in blood ATH-063 concentrations throughout the study"The results of our first-in-human clinical trial of ATH-063 exceeded our high expectations," said Dimitrios Iliopoulos, PhD, MBA, Founder, President & CEO, Athos. "We used the Athos AI2 drug development platform to identify a previously unrecognized and novel therapeutic target, to create ATH-063, and to preclinically predict the compound's proposed mechanisms of action. We are delighted that these Phase 1 results serve as clinical verification for the predictions made by the Athos AI2 computational engine" added Dr. Iliopoulos."Our Phase 1 data showed that once daily, oral dosing of ATH-063 was well tolerated and showed expansion of Tregs," commented Allan Pantuck, MD, MS, FACS, Chairman, Founder & CMO. "We are excited to move to our next stage of clinical development in subjects with moderately to severely active ulcerative colitis. The rapid pace of the ATH-063 program, from initial target identification to a completed Phase 1 trial, was enabled by the use of our innovative approach to leveraging Artificial Intelligence for drug development."About ATH-063ATH-063 is a novel, investigational, AI-generated, oral, small molecule, G9A inhibitor in development for the treatment of inflammatory bowel disease and other autoimmune diseases. G9A is a central hub on a gene network that was identified by the Athos AI2 platform through the integration of multi-omic and longitudinal clinical data from Athos' IBD biorepository. ATH-063 is designed to directly target G9A enzymatic activity in human CD4 T cells and GI epithelial cells, acting both by suppressing pro-inflammatory responses through expansion and activation of regulatory T cells and inducing direct mucosal healing through regulation of tight junction proteins.About Athos TherapeuticsAthos Therapeutics is a clinical stage biotechnology company seeking to develop potential first-in-class therapeutics that significantly impact the lives of patients with autoimmune disorders and chronic inflammatory diseases. The Athos drug development platform begins with over 25,000 high-quality patient samples sourced from premier global hospital systems. Athos' AI2 platform identifies novel drug targets by integrating multi-omic and longitudinal clinical datasets and matches them to its small molecule computational chemistry platform. The AI2 platform includes the Athos data lake, singular well-established omics workflows, and an integrative deep machine learning engine. The company's lead drug compound is ATH-063, an investigational, oral small molecule G9A inhibitor for inflammatory bowel disease.Athos is also developing a pipeline of additional small molecule approaches for various autoimmune diseases.Additional information about Athos Therapeutics can be found at https://athostx.com/Contact:Athos Therapeutics, Inc.Keith Hoffman, PhD, Chief Business Officerkhoffman@athostx.comSOURCE: Athos Therapeutics, Inc. Copyright 2024 ACN Newswire via SeaPRwire.com.

The Electronics Fair and electronicAsia attract more than 60,000 buyers

- The two major electronics fairs concluded today, attracting over 60,000 industry buyers from 136 countries and regions- 53% of respondents in an on-site survey expect overall sales to increase over the next 12-24 months, while 43% expect sales to remain stable- Most respondents believe there is a “very promising” or “promising” market potential for wearable electronic products (65%) and robotics technology (59%)HONG KONG, Oct 16, 2024 - (ACN Newswire via SeaPRwire.com) - The Hong Kong Electronics Fair (Autumn Edition), organised by the Hong Kong Trade Development Council (HKTDC), and electronicAsia, jointly organised by the HKTDC and MMI Asia Pte Ltd, concluded their physical exhibitions today.The four-day events attracted more than 60,000 industry buyers from 136 countries and regions. The number of buyers from Malaysia, Türkiye, Argentina and the UAE increased from last year. This reflects the exhibitions' status as important sourcing platforms for the industry.Sophia Chong, Deputy Executive Director of the HKTDC, said: "The global trend towards smart living is driving demand for innovative products and solutions. The Electronics Fair and electronicAsia serve as efficient platforms for the industry, enabling exhibitors to showcase their electronic products and technology solutions to buyers. We are pleased to see exhibitors and buyers successfully exploring business opportunities at the exhibitions, which are expediting Hong Kong's development into an international innovation and technology (I&T) centre.”In late October, the HKTDC will host the Hong Kong International Lighting Fair (Autumn Edition), Hong Kong International Outdoor and Tech Light Expo and ECO Expo Asia to create more cross-industry business opportunities.Industry optimistic about India, the Middle East, Latin AmericaAn independent survey agency commissioned by the HKTDC interviewed 1,091 Electronics Fair buyers and exhibitors about growth prospects for the industry. 53% of respondents expect overall sales to increase in the next 12-24 months, while 43% anticipate that they will remain stable. Most respondents believe that the electronics industry has the most growth potential in emerging markets, such as India, the Middle East and Latin America over the next two years, followed by Korea, Mainland China, Australia and the Pacific Islands.In terms of trends in electronic products, most respondents believe there is a “very promising” or “promising” market potential for wearable electronic products (65%) and robotics technology (59%).Meanwhile, 56% of respondents believe that the market potential for e-sports products and equipment is high. Most respondents consider these products to have the greatest growth potential in North America and Northern and Western Europe.Exhibitors attract quality buyers at fairsThis year's Electronics Fair featured more than 20 zones, gathering the latest electronic products and innovative solutions from global exhibitors in areas such as smart cities, smart mobility, gerontechnology and digital entertainment.First-time exhibitor and Founder of Zunosaki Limited, Newmen Ho, promoted the company's hand rehabilitation robot in the Startup Zone, seeking Mainland China and overseas distributors, partners and investors. In the first half of the exhibition, he met potential buyers from Taiwan’s nursing homes and from Korea. Additionally, a buyer from India expressed interest in applying the company's robotic hand technology across different industries.Hong Kong's renowned consumer electronics brand Momax achieved impressive results at the fair. The company's Founder and CEO John Cheng stated that in the first two days of the Fair, the team met some 60 buyers from the Asia-Pacific region and Europe. Momax also formed a long-term partnership with a publicly listed company in Papua New Guinea and is currently discussing an initial order valued at US$50,000.Additionally, through HKTDC’s Click2Match smart business matching platform, the company connected with another quality buyer from Australia, with the intent to collaborate long-term. Mr Cheng said: "Hong Kong's exhibitions are world-class, featuring high-quality buyers from a diverse range of countries. This year's Autumn Electronics Fair saw a significant turnout, and the buyers were very engaged. We will definitely participate again next year."Dongguan Maochang Printed Circuit Board Ltd, which develops technological solutions, participated in electronicAsia to stay updated on industry trends and identify potential buyers. The company's Sales Director, Michael Tsang, said: "Expanding onto the international stage is our primary goal for participating in the exhibition. I am glad that we met with over 200 potential buyers in the first three days to gain a deeper understanding of customer needs."Buyer seeks new products to expand marketVinal Patel, Chief Commercial Officer of UK buyer Brand Collective, has been attending the Electronics Fair for over 20 years. During the first two days of this year's fair, he secured over US$2 million worth of purchases, including charging cables, power banks and wireless speakers from two exhibitors. He is also considering expanding the range of products he distributes after discovering new offerings at the Fair. Mr Patel said: "The line-up at the exhibition gets better every year, even more impressive than before the pandemic. I will definitely participate in the Electronics Fairs in April and October in the future."Turkish buyer and Co-founder of Robotistan Elektronik Tic AS, Yusuf Gündogdu, visited electronicAsia with a purchasing budget of around U$100,000-200,000 for electronic products. He said: "The Electronics Fair is the best opportunity for me to interact face-to-face with exhibitors from around the world. I always find the best prices here. Meeting the founders of start-ups in the Startup Zone excites me. These companies are poised to become some of the best in the future and will drive market development through innovation, which I eagerly look forward to."The organisers held 78 events and forums during the exhibitions, inviting industry leaders to share unique insights and the latest industry information. These events included the Symposium on Innovation & Technology, Hong Kong Electronic Forum and Reliability Assurance for Electronic Systems Forum. Other on-site activities catered to start-ups, including investment matching, the Hong Kong Value Creation for Technology: Pitching Competition, Meet the Mentors sessions and Start-up Smart Launch.Under the EXHIBITION+ hybrid model, exhibitors and buyers can use the Click2Match smart business matching platform to conduct online meetings, in addition to attending the physical fair. Exhibitors and buyers can still explore business opportunities and conduct online negotiations through Click2Match until 23 October.Photo Download:https://bit.ly/3BVmX2RHong Kong Electronics Fair (Autumn Edition) and electronicAsia successfully concluded. The four-day events attracted over 60,000 buyers from 136 countries and regionsThis year's Symposium on Innovation & Technology, themed 'When Two Worlds Collide: The Confluence of Digital Twins & Real-Life Applications', featured heavyweight guests and attracted numerous industry professionalsThe Hall of Fame gathered consumer electronic products from renowned brands worldwide. Among them, Asia Kingston (HK) Limited, specialising in brand licensing, presented a gaming chair featuring the NASA logoLocal brands, including well-known electronic brand Momax, promoted their products to global buyersThe Tech Hall showcased products using a variety of cutting-edge technologies, including 3D printing, Internet of Things, robotics, AR and XRThis year's Electronics Fair introduced a Digital Entertainment Experience Zone, where buyers could try and explore products on-siteThe concurrent electronicAsia featured multiple zones, exhibiting products, such as electronic components and parts, keyboards and switches, power supply equipment and moreThe Hong Kong Electronic Forum, co-organised by the HKTDC, MMI Asia Pte Ltd and the Hong Kong Electronic Industries Association, was themed “Innovation Unleashed: The Intersection of Microelectronics, AI, and Open-Source Ecosystems”WebsitesHong Kong Electronics Fair (Autumn Edition):  hkelectronicsfairae/enelectronicAsia: electronicasia/enMedia enquiriesPlease contact the HKTDC’s Communications & Public Affairs Department:Katy WongTel: (852) 2584 4524Email: katy.ky.wong@hktdc.orgSnowy ChanTel: (852) 2584 4525Email: snowy.sn.chan@hktdc.orgHKTDC Media Room: https://mediaroom.hktdc.com/enAbout the HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong ’s trade. With 50 offices globally, including 13 in Mainland China, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly SMEs, in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via trade publications, research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. Copyright 2024 ACN Newswire via SeaPRwire.com.

GTJAI Signed the Good Employer Charter Again

HONG KONG, Oct 17, 2024 - (ACN Newswire via SeaPRwire.com) - Guotai Junan International Holdings Limited (“Guotai Junan International”, “GTJAI”, the “Company” or the “Group”, stock code: 1788.HK) is pleased to announce that the Company has participated in the Good Employer Charter Scheme launched by the Hong Kong Labour Department for the sixth consecutive year, committed to adopting good personnel management practices and creating a family-friendly working environment for employees.The Good Employer Charter 2024 features the theme of “Supportive Family-friendly Good Employer”. Employers of different industries and scales are encouraged to adopt and enhance employee-oriented family-friendly employment practices, putting themselves in the employees’ shoes in discharging both work and family obligations, so as to create a family-friendly working environment. This signing of the Good Employer Charter demonstrates the Company’s efforts in employee care and creating a harmonious and inclusive working environment.GTJAI has always cared for its employees. Adhering to the business philosophy of “Talent as the First Resource” and pursuing the talent concept of “People-oriented, Collaborative Cooperation”, GTJAI considers employees as its core asset and has always been devoted to creating an inclusive and healthy working environment, and providing adequate resources to support employees’ growth and development. In the future, GTJAI will continue to strive to improve employee satisfaction, create a more friendly working environment, and contribute to building a harmonious and inclusive society. Copyright 2024 ACN Newswire via SeaPRwire.com.

朝鲜将与韩国的边界变成“永恒的堡垒”

(SeaPRwire) -   破坏道路和铁路是“对首尔的挑衅做出的不可避免和合法的回应”,平壤表示。 朝鲜已经誓言,与“绝对敌对国家”韩国的边境将成为“永恒的堡垒”,同时证实了有关破坏与邻国道路和铁路联系的报道。 朝鲜中央通讯社 (KCNA) 周四报道称,本周早些时候,平壤部队在该边境东西段沿线炸毁了 60 米长的道路和铁路路段,“作为南北逐步完全分离的一部分”。 该通讯社援引朝鲜国防部代表的话说:“将采取进一步措施,将封锁的南部边境变成永恒的堡垒。” 韩国联合参谋本部 (JCS) 周二表示,朝鲜在两国之间的军事分界线以北引爆了部分京义线和东海线道路。 切断道路和铁路连接是“不可避免的,也是合法的措施,符合朝鲜宪法的要求,朝鲜宪法明确将韩国定义为绝对敌对国家”,KCNA 表示。 这也是对“严重安全局势的回应,由于敌对势力的严重军事政治挑衅,安全局势正处于不可预测战争的边缘”,该通讯社补充说。 这似乎是朝鲜宪法首次正式将韩国定义为“敌对国家”。这一事态发展是在朝鲜最高人民会议上周会议之后发生的,据报道,这次会议旨在修订该国的基本法律。 朝鲜领导人金正恩在 1 月份对该国议会的讲话中表示,与韩国的统一不再是选择,并敦促修改宪法,以便将韩国宣布为一个独立的“敌对”国家。 周五,朝鲜指责韩国本月仅三次就派出无人机投放宣传传单飞越平壤。首尔既没有证实也没有否认无人机飞行,但警告说,如果朝鲜通过攻击韩国进行报复,朝鲜将看到“其政权的终结”。 平壤在几周前美韩联合军演后首次谈到切断朝韩道路和铁路,朝鲜将此描述为“针对侵略的挑衅性战争演习”。此后,朝鲜军队一直在加强其边界一侧的防线,部署前线火炮、军队单位、地雷和障碍物。 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布,覆盖超过6,500个媒体库、86,000名编辑和记者,以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。

Eco Expo Asia opens at AsiaWorld-Expo in late October

- Eco Expo Asia is expected to attract over 300 exhibitors from 11 countries and regions with new exhibitor groups from Anhui Province and Norway- The Expo will feature three focal points: New Energy, Waste Management and Circular Economy, and ESG-related Services, in pursuit of achieving the dual carbon goals- Government officials, industry experts and business leaders from various countries and regions, including Belt and Road countries will attend the Eco Asia Conference- Talks and workshops on the last day of the Expo (2 November) will be open to the public for freeHONG KONG, Oct 17, 2024 - (ACN Newswire via SeaPRwire.com) - Eco Expo Asia 2024, jointly organised by the Hong Kong Trade Development Council (HKTDC) and Messe Frankfurt (HK) Ltd and co-organised by the Environment and Ecology Bureau of the Government of the Hong Kong Special Administrative Region (HKSAR), will be held at AsiaWorld-Expo from 30 October to 2 November. The last day of the event will be open to the public for free.To extend the sourcing journey, exhibitors and buyers worldwide can connect via the Click2Match virtual business matching platform from 23 October to 9 November.HKTDC Assistant Executive Director Jenny Koo said: "In the face of climate change, countries and regions have been actively propelling carbon reduction policies and sustainable development. China, for instance, set carbon reduction and neutrality goals in 2020 and has been advocating the development of new quality productive forces. The Hong Kong SAR Government is also committed to achieving carbon neutrality before 2050, and the development of related industries has become increasingly diversified, laying a strong foundation for Hong Kong’s sustainable development. Themed Fostering Green Innovations for Carbon Neutrality, the 19th edition of Eco Expo Asia will bring together international exhibitors and industry professionals to showcase cutting-edge innovations and technologies that aim to achieve dual carbon goals.”Speaking at the press conference, the Deputy Director of the Environmental Protection Department of the HKSAR Government, Fong Kin-wa, expressed: "We hope the Eco Expo Asia could share with visitors and exhibitors from around the world, including Belt and Road countries and ASEAN countries, the latest green innovation for achieving carbon neutrality, with a view to promoting exchange and cooperation between governments and trade sectors on boosting green & low-carbon transformation, achieving sustainable development, and leading Hong Kong towards carbon neutrality.”Converging international exhibitors and government officials at Eco Expo AsiaThis year’s Expo is expected to attract over 300 exhibitors from 11 countries and regions including Mainland China, Hong Kong, Macao, Taiwan, Singapore, Germany, Finland, Norway, the Netherlands, the United States and Canada. Several provinces and cities from Mainland China will form pavilions, including the return of Guangzhou and Shenzhen. The Anhui Pavilion will debut with technologies focused on air quality, water treatment and quality management as well as new energy materials and equipment. Supported by Innovation Norway, the debut group participation from Norway will showcase technologies for water quality management and waste treatment.The Eco Asia Conference, held during the first three days of the exhibition, will provide a platform for government officials, industry experts and business leaders from various countries and regions to discuss key trends, including energy projections, green building technologies and the circular economy. The conference is supported by the Ministry of Ecology and Environment, National Development and Reform Commission, and Ministry of Industry and Information Technology of the People’s Republic of China. Officials from Belt and Road countries, including Malaysia, Laos, Saudi Arabia, Myanmar, Brunei and Vietnam will also attend the conference.Three focal points in pursuit of dual carbon goalsTo achieve dual carbon goals, the development of green energy and green transportation has become a global trend. New energy is a focus of this year’s exhibition and many innovative new energy-related products and technologies will be featured. For example, Hong Kong’s first hydrogen fuel cell street-cleaning vehicle will be showcased at the booth hosted by the Environment and Ecology Bureau in conjunction with other HKSAR government units.The Inner Mongolia Pavilion will showcase cutting-edge solutions in environmental protection, ecological restoration and new energy. Innovative technical solutions, such as hydrogen purification systems and carbon capture and storage equipment, will be highlighted at the Canada Pavilion. In the Green Transportation zone, GMI Motors Ltd and first-time exhibitor Xiamen Golden Dragon Bus Co. Ltd will present a variety of electric vehicles. Chun Yang International (HK) Company Ltd will demonstrate fast charging and mini wall-mounted EV chargers catering to different needs.Waste Management and Circular Economy is a second focal point of the Expo, with exhibitor Smart Farming HK Ltd showcasing fish feed made from food waste and a sustainable fish farming concept. First-time exhibitor Nanda (Hong Kong) Technology Corporation Ltd will feature a food waste biodegradation machine that can process up to 36,000 kg of food waste per day.The Sustainable Restaurant Awards 2024, the first of its kind in Hong Kong's F&B industry to recognise restaurants based on their carbon footprint, will be presented on the third day of the Expo.The third focal point of the Expo is ESG-related services which is experiencing strong demand.  Several world-leading certification and consultancy companies will exhibit for the first time, including SGS Hong Kong Ltd, Intertek Testing Services Hong Kong Ltd, TUV Rheinland Hong Kong Ltd and BSI Pacific Ltd to present their testing and certification services as well as ESG consulting and training programmes. ESG AI, an innovative tool launched by China Energy Conservation & Environmental Protection (Hong Kong) Investment Co. Ltd, makes use of big data analysis and other technologies to generate regulatory-compliant ESG reports in one click.Nurturing talent to inject fresh energyEco Expo Asia has long been a platform for start-ups to showcase their latest innovations. Hong Kong Science and Technology Parks Corporation will showcase products and technologies from 10 start-ups related to green transport, circular economy and energy efficiency.In the popular Start-up Zone, exhibitor Ezygreenpak Ltd will demonstrate its patented water-soluble non-woven packaging material that can be completely dissolved in 90°C hot water without leaving any harmful residue. BSF Innovation Ltd's organic green building powder, consisting of fibre and calcium extracted from insect shells and food waste, can be blended with traditional building materials to make eco-bricks, reducing the manufacturing process carbon emissions by around 40%.A series of seminars and workshops on Public DayTo encourage residents to adopt green living practices, talks and workshops will be held on the last day of the Expo (2 November), which are free and open to the public. A highlight will be the Dialogue with the Secretary for Environment and Ecology for school students. Experts will share their strategies and experience in tackling extreme weather. The public can also participate in a variety of green workshops and shop for green products at Green Mart.Photo download: https://bit.ly/3BWSrpjJenny Koo, Assistant Executive Director of the HKTDC, introduced Eco Expo Asia highlights at the press conference. She said Hong Kong’s environmental-related industries were expanding in diversity, establishing the groundwork for the city’s sustainable development.The Chief Executive’s 2024 Policy Address released yesterday emphasises the need to promote the development of new energy and expand the electric vehicle charging network. Ms Koo stated that the HKTDC has been committed to promoting sustainable development in the business sector. In October, the HKTDC will work closely with the Environmental and Ecology Bureau to hold Eco Expo Asia, and provide support services and sourcing platforms to assist industry players in promoting and sourcing green products and solutions. In addition to Eco Expo Asia, the HKTDC aims to facilitate international connections through large-scale flagship events, promoting Hong Kong's role as an international centre for green finance and green technologyJenny Koo, Assistant Executive Director, HKTDC (centre); Fong Kin-wa, Deputy Director of the Environmental Protection Department of the HKSAR Government (left), and Judy Cheung, Deputy General Manager, Messe Frankfurt (HK) Ltd (right), attended the press conferenceGMI Motors Ltd displayed a brand-new, 32-seater electric bus with a large capacity batteryStart-up Ezygreenpak Ltd demonstrated its innovative water-soluble non-woven packaging material that can completely dissolve in 90°C hot waterTen companies resident at Hong Kong Science and Technology Parks Corporation sites will take part in the exhibition. Growgreen Ltd and One Energy (HK) Ltd showcased products related to circular economy and green transportation at the press conferenceSmart Farming HK Ltd introduced food waste recycled feed and fish farming sustainabilityWebsiteEco Expo Asia: www.ecoexpoasia.comMedia enquiriesPlease contact the HKTDC’s Communications and Public Affairs Department:Stanley SoTel: (852) 2584 4049Email: stanley.hp.so@hktdc.orgClayton Lauw     Tel: (852) 2584 4472  Email: clayton.y.lauw@hktdc.orgThe HKTDC’s Media Room:  http://mediaroom.hktdc.com/enAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With 50 offices globally, including 13 in Mainland China, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences, and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus.Background information on Messe FrankfurtThe Messe Frankfurt Group is one of the world’s leading trade fair, congress and event organisers with their own exhibition grounds. With a workforce of some 2,160 people at its headquarters in Frankfurt am Main and in 28 subsidiaries, it organises events around the world. Group sales in financial year 2022 were around €454 million. We serve our customers’ business interests efficiently within the framework of our Fairs & Events, Locations and Services business fields. One of Messe Frankfurt’s key strengths is its powerful and closely knit global sales network, which covers around 180 countries in all regions of the world. Our comprehensive range of services – both onsite and online – ensures that customers worldwide enjoy consistently high quality and flexibility when planning, organising and running their events. We are using our digital expertise to develop new business models. The wide range of services includes renting exhibition grounds, trade fair construction and marketing, personnel and food services. Sustainability is a central pillar of our corporate strategy. Here, we strike a healthy balance between ecological and economic interests, social responsibility and diversity.For more information, please visit our website at: www.messefrankfurt.com/sustainability. With its headquarters in Frankfurt am Main, the company is owned by the City of Frankfurt (60 percent) and the State of Hesse (40 percent). For more information, please visit our website at: www.messefrankfurt.com Copyright 2024 ACN Newswire via SeaPRwire.com.

Graphene Manufacturing Group (GMG) Provides Commercialisation Update on Energy Savings Coating THERMAL-XR(R)

Brisbane, Queensland, Australia--(ACN Newswire via SeaPRwire.com - October 16, 2024) - Graphene Manufacturing Group Ltd. (TSXV: GMG) ("GMG" or the "Company") is pleased to provide a business update on the commercialisation progress of THERMAL-XR® Powered by GMG Graphene.CUSTOMER ENGAGEMENT UPDATEGMG continues to carry out both Supply and Service Coating for various Air Conditioning Manufacturers, Distributors, Contractors and end equipment owners - including the large HVACR condensing units showing the black coating of THERMAL-XR on the condenser coils seen in Figure 1.Figure 1: GMG Team Members in front of large HVACR condensing units coated with THERMAL-XRTo view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/8082/226793_4a202364a43cd862_001full.jpgAt an event on 4th October 2024 in Brisbane, Australia that included the broad participation of HVAC industry representatives, GMG successfully RE-launched THERMAL-XR® ENHANCE. The focus of the event was on Thermal-XR's unique heat transfer and corrosion protection capabilities. When first developed, the product was named THERMAL-XR® RESTORE because the Company believed its principal benefit was to restore the heat transfer capabilities of existing installed air conditioners. However, GMG has since proved with third party verification that the product can also enhance the heat transfer of new equipment; hence the re-branding to THERMAL-XR® ENHANCE.As a result, GMG now believes that THERMAL-XR® ENHANCE has exciting opportunities with HVAC Original Equipment Manufacturers ("OEMs") in addition to its potential in the HVAC aftermarket. Over the past several months, GMG has completed on-site testing of THERMAL-XR® with global Air Conditioning Manufacturers in China and the USA for potential introduction into their factories. While further customer testing will be required, GMG believes early results are promising.Apart from applications in the HVAC industry, the unique heat transfer capabilities of THERMAL-XR® ENHANCE has also led to potential new applications in a wide range of industries where reducing heat is important. For example, customer managed Third Party Laboratory Testing with THERMAL-XR® is now being done with companies that operate LNG facilities; companies that manufacture electronic products; and companies that produce motors for the industrial and automotive markets. Further testing will be required to confirm the benefits of using THERMAL-XR® ENHANCE in such applications.Figure 2: RE-LAUNCH of THERMAL-XR® ENHANCETo view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/8082/226793_4a202364a43cd862_002full.jpgAs shown in Figure 2, THERMAL-XR® ENHANCE will now be available in 5 litre pails, instead of the original 10 litre containers. Customers have expressed their preference for lighter weight pails because they believe they are easier to lift onto roof tops for spraying in-situ air conditioners. Generally, 5 Litres of THERMAL-XR can be used to spray up to 5 small to medium size air conditioners, covering approximately 50 square metres of solid plate.As previously announced, GMG and Nu Calgon have signed an agreement and are working with a consultant to prepare and submit a Pre-Manufacture Notice ("PMN") in conjunction with its USA Environmental Protection Agency's ("EPA") application to import and sell in the USA. The PMN application is expected to be submitted before the end of October, and the approval is expected to take less than 12 months. The PMN will be substantially different from the Low Volume Exemption ("LVE") PMN that was previously submitted by GMG. Unlike the LVE PMN application that was limited to 10 tons per annum and one application technique in the HVAC sector, the PMN EPA approval that GMG is now seeking will not be limited by volume, application and any one particular sector.INDUSTRY RECOGNITIONTHERMAL-XR® is a finalist in the AIRAH Product of the Year - to be announced on 21st November 2024. AIRAH, the Australian Institute of Refrigeration, Air Conditioning and Heating, is the peak body representing the HVAC&R industry in Australia. Officially incorporated by guarantee on March 29, 1920, AIRAH celebrated its Centenary anniversary in 2020.The AIRAH Awards provide our industry with the opportunity to reflect, applaud, and raise a toast to our peers and their achievements - from promising future leaders to established sector veterans; from the finest new projects to the best retrofits; as well as the greatest in refrigeration, renewable energy, and research. Independent industry specialists determine a shortlist of finalists, from which a winner is selected by an expert judging panel. This rigorous and impartial process makes the AIRAH Awards the most highly prized accolades in Australia's HVAC&R building services industry.To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/8082/226793_4a202364a43cd862_003full.jpgGMG's Managing Director and CEO, Craig Nicol, commented: "We believe GMG continues to make good progress in testing its products in large global OEM's for various types of products in various applications whilst our technical understanding of the coating improves - creating an exciting cycle of innovation and learning with our customers and how we make the graphene and coating, how it is applied and also how it is marketed and sold."GMG's Chairman and Director, Jack Perkowski, commented: "THERMAL-XR® testing in so many of these applications is very exciting to see and I am encouraged by its potential for progress in these markets."TEAM UPDATEGMG would like to thank Bobby Bran, Chief Projects Officer ("CPO"), for his near 6-year service at the Company. In the Company's continued efforts to transform into a commercial operation, the Company has decided to outsource major project activity going forward and as such will no longer need a CPO.On behalf of GMG and its Board of Directors, Craig Nicol and Jack Perkowski would like to thank Bobby for his dedication and service during his near 6-year tenure at the Company.About THERMAL-XR® powered by GMG Graphene:THERMAL-XR® COATING SYSTEM is a unique method of improving the conductivity of corroded heat exchange surfaces and improving and maintaining the performance of new units at peak levels. The process coats and protects heat exchange surfaces while improving and rebuilding the lost corroded thermal conductivity and increasing the heat transfer rate by leveraging the physics of GMG Graphene, resulting in an efficiency improvement and a potential power reduction.THERMAL-XR RESTORE® is powered by GMG Graphene. PATENT PENDINGAbout GMG www.graphenemg.comGMG is a clean-technology company which seeks to offer energy saving and energy storage solutions, enabled by graphene, including that manufactured in-house via a proprietary production process. GMG has developed a proprietary production process to decompose natural gas (i.e. methane) into its elements, carbon (as graphene), hydrogen and some residual hydrocarbon gases. This process produces high quality, low cost, scalable, 'tuneable' and low/no contaminant graphene suitable for use in clean-technology and other applications.The Company's present focus is to de-risk and develop commercial scale-up capabilities, and secure market applications. In the energy savings segment, GMG has focused on graphene enhanced heating, ventilation and air conditioning ("HVAC-R") coating (or energy-saving coating), lubricants and fluids.In the energy storage segment, GMG and the University of Queensland are working collaboratively with financial support from the Australian Government to progress R&D and commercialization of graphene aluminium-ion batteries ("G+AI Batteries").GMG's 4 critical business objectives are:Produce Graphene and improve/scale cell production processesBuild Revenue from Energy Savings ProductsDevelop Next-Generation BatteryDevelop Supply Chain, Partners & Project Execution CapabilityFor further information please contact:Craig Nicol, Chief Executive Officer & Managing Director of the Company at craig.nicol@graphenemg.com, +61 415 445 223Leo Karabelas at Focus Communications Investor Relations, leo@fcir.ca, +1 647 689 6041Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accept responsibility for the adequacy or accuracy of this news release.Cautionary Note Regarding Forward-Looking Statements This news release includes certain statements and information that may constitute forward-looking information within the meaning of applicable Canadian securities laws. Forward-looking statements relate to future events or future performance and reflect the expectations or beliefs of management of the Company regarding future events. Generally, forward-looking statements and information can be identified by the use of forward-looking terminology such as "intends", "expects" or "anticipates", or variations of such words and phrases or statements that certain actions, events or results "may", "could", "should", "would" or will "potentially" or "likely" occur. This information and these statements, referred to herein as "forward‐looking statements", are not historical facts, are made as of the date of this news release and include without limitation, the potential for THERMAL-XR® to enable energy producers to produce additional energy more efficiently, the potential for THERMAL-XR® ENHANCE to enhance the heat transfer of new equipment and its opportunities with HVAC industry and other industries where reducing heat is important, the timing of submission of the Company's PMN application, the receipt, timing and nature of approval by the EPA of the PMN application, the Company's goal of achieving optimal production line performance for THERMAL-XR® and the entering of full production. Such forward-looking statements are based on a number of assumptions of management, including, without limitation, assumptions regarding the development of extensions and enhancements to the THERMAL-XR® portfolio into a wider range of applications, that energy producers will be able to derive the expected benefits from the Company's products, that the Company's PMN application will be submitted on the timetable anticipated, that the EPA will approve the PMN application and on the timing anticipated, that the content of the EPA's approval will be as anticipated, and that the Company will be able to achieve optimal production line performance for THERMAL-XR® and enter full production. Additionally, forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of GMG to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation: that there will be no developments of extensions or enhancements to the THERMAL-XR® portfolio into a wider range of applications, that energy producers will not derive the expected benefits from the Company's products, that the Company's PMN application will not be submitted on the timetable anticipated or at all, that the EPA will not approve the PMN application on the timing anticipated or at all, that the content of the EPA's approval will not be as anticipated, that the Company will be unable to achieve optimal production line performance for THERMAL-XR® or enter full production, risks relating to the extent and duration of the conflict in Eastern Europe and its impact on global markets, the volatility of global capital markets, political instability, the failure of the Company to obtain regulatory approvals, attract and retain skilled personnel, unexpected development and production challenges, unanticipated costs and the risk factors set out under the heading "Risk Factors" in the Company's annual information form dated October 3, 2024 available for review on the Company's profile at www.sedarplus.ca.Although management of the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking statements or forward-looking information, there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements and forward-looking information. Readers are cautioned that reliance on such information may not be appropriate for other purposes. The Company does not undertake to update any forward-looking statement, forward-looking information or financial out-look that are incorporated by reference herein, except in accordance with applicable securities laws. We seek safe harbor.To view the source version of this press release, please visit https://www.newsfilecorp.com/release/226793 Copyright 2024 ACN Newswire via SeaPRwire.com.

A Joint Regional Cohort Study by Shimadzu, Eisai, Oita University, and Usuki City Medical Association

Shimadzu Corporation, Eisai Co., Ltd., Oita University, and Usuki City Medical Association have demonstrated the utility of blood biomarkers in predicting the accumulation of amyloid beta (Aβ)(1) in the brain, a noted cause of Alzheimer’s disease(2), in a cohort study conducted in Usuki City, Oita from November 2022. A research paper reporting the details of this study was published on October 10, 2024, in the journal Alzheimer’s & Dementia: Translational Research & Clinical Interventions.This joint research attempts to develop Japan’s first diagnostic workflow for mild cognitive impairment (MCI) due to Alzheimer’s disease and mild dementia based on blood biomarkers. Comprising a phase 1 and phase 2 study, the phase 1 study uses frozen samples of blood plasma from a regional cohort collected by a prospective cohort study performed in Usuki City between 2015 and 2019 to evaluate the utility of blood biomarkers in predicting Aβ accumulation in the brain. The phase 2 study is a prospective study that uses blood plasma samples collected from 100 newly recruited subjects through diagnostic workflows adopted at all levels of health care, from primary care physicians to specialists certified by dementia-related societies, to evaluate the psychological impact on participants of different results and who discloses them.The research paper primarily compiles results from the phase 1 study. The ability of blood biomarkers to predict the results of amyloid PET scans(3) was evaluated in terms of an area under the curve (AUC) value. Blood biomarker measurements performed by Shimadzu resulted in an AUC value of 0.94 and identified PET-positive patients in the regional cohort with a high degree of accuracy. The joint research also revealed the possibility to predict the progression of clinical symptoms using baseline blood biomarker results, i.e., the progression from MCI due to Alzheimer's disease to Alzheimer's dementia from analysis of participant data over a seven-year observation period. Blood biomarker testing is less invasive than amyloid PET and cerebrospinal fluid testing(4), and could reduce patient stress and help predict the future onset of dementia if used as an alternative to these two diagnostic methods. The data collection stage of phase 2 is complete with plans in place to carry out data analysis and draft an overall report of the results of both phases of the joint research.The four parties involved in this joint research are committed to building an ecosystem that improves the early diagnosis of Alzheimer’s through diagnostic workflows adopted at all levels of health care from primary care physicians to specialists who are members of dementia-related societies, and through this research develop social infrastructure that ensures patients and their families live happy and fulfilling lives.Comment by Noriyuki Kimura, an Associate Professor at the Department of Neurology, Faculty of Medicine, Oita UniversityTreatment of Alzheimer’s disease is approaching a new turning point with the emergence of anti-amyloid beta antibodies that will require the diagnosis of Alzheimer’s disease at the MCI or early dementia stage. Biomarker-based tests to detect amyloid accumulation in the brain include amyloid PET scans and cerebrospinal fluid testing, but PET scans are expensive and cerebrospinal fluid testing is highly invasive. Blood biomarker testing is low-cost and less invasive, and its adoption promises to reduce the financial and physical burden on patients.(1) Amyloid beta is a protein believed to cause Alzheimer’s disease that accumulates in the brain to form senile plaques beginning around 20 years before the onset of Alzheimer’s disease.(2) Alzheimer’s disease is the most common cause of dementia and its key pathological hallmarks are senile plaques, neurofibrillary tangles, and neuronal cell death.(3) Amyloid PET is a brain imaging test that can visualize amyloid beta accumulation in the brain.(4) Cerebrospinal fluid testing collects cerebrospinal fluid and tests it for amyloid-β 42, amyloid-β 40, phosphorylated tau protein, and total tau protein, which are biomarkers of Alzheimer’s disease.Research Paper InformationJournal name: Alzheimer's & Dementia: Translational Research & Clinical InterventionsTitle of paper: Plasma amyloid beta biomarkers predict amyloid positivity and longitudinal clinical progression in mild cognitive impairment.Authors: Takuya Ataka, Noriyuki Kimura, Naoki Kaneko, Teruaki Masuda, Yosuke Takeuchi, Kenichi Yabuuchi, Takeshi Mizukami, Tsukasa Takeuchi, Temmei Ito, Hideaki Tasai, Takehiko Miyagawa, Shunya Hanai, Shinichi Iwamoto, and Etsuro MatsubaraDOI: 10.1002/trc2.70008Related InformationNovember 22, 2022 Press releaseTo Develop Japan’s First Blood Biomarker-Based Diagnostic Workflow for DementiaShimadzu, Eisai, Oita University, and Usuki City Medical Association Commence Joint Researchwww.eisai.com/news/2022/news202280.html For Press and Media Inquiries, Please Contact:Shimadzu CorporationCorporate Communication Department Phone: +81-75-823-1110Eisai Co., Ltd.Public Relations Department Phone: +81-3-3817-5120Oita UniversityDepartment of Neurology, Faculty of Medicine Phone: +81-97-586-5814Usuki City Medical AssociationUsuki City Medical Association Office Phone: +81-972-63-0099 Copyright 2024 JCN Newswire via SeaPRwire.com.

国泰君安国际再次签署《好雇主约章》 营造和谐共融工作环境

香港, 2024年10月17日 - (亚太商讯 via SeaPRwire.com) - 国泰君安国际控股有限公司("国泰君安国际"、"公司"或"集团",股份代号:1788.HK)欣然宣布,公司连续第六年参与由香港劳工处推出的《好雇主约章》计划,致力于采取良好的人事管理措施,并为员工营造家庭友善的工作环境。《好雇主约章》2024以「为你『家』『友』好雇主」为主题,鼓励各行业及不同规模的雇主推行及优化以雇员为本的家庭友善雇佣措施,将心比己体谅雇员兼顾工作及家庭的责任,缔造家庭友善的工作环境。此次签署《好雇主约章》,展现了公司在员工关怀及营造和谐共融工作环境方面所做出的努力。国泰君安国际一直关爱员工,秉承「人才是第一资源」的经营理念,奉行「以人为本,协同协作」的人才理念,视员工为企业的核心资产,打造包容、健康的工作环境,并提供充足的资源支持员工的成长与发展。未来,国泰君安国际将继续致力于提升员工满意度,营造一个更加友善和谐的工作环境,为缔造和谐共融的社会贡献力量。 Copyright 2024 亚太商讯 via SeaPRwire.com.

Update on Regulatory Review of Lecanemab for Early Alzheimer’s Disease in Australia

TOKYO and CAMBRIDGE, Mass., Oct 17, 2024 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. and Biogen Inc. announced today that the Therapeutic Goods Administration (TGA) of Australia issued a public statement about the initial decision not to register the humanized anti-solubleaggregated amyloid-beta (Aβ) monoclonal antibody lecanemab for the treatment of patients with mild cognitive impairment (MCI)due to Alzheimer’s disease (AD) and mild AD dementia.Eisai will request a reconsideration of this decision under Section 60* of the Therapeutic Goods Act within 90 days to make lecanemab available for eligible people living with early AD in Australia. Following Eisai’s request for review, the TGA will issue a final decision within 60 days of receiving Eisai’s request.Lecanemab is already approved in the United States, Japan, China, South Korea, Hong Kong, Israel UAE and Great Britain, and is being marketed in the U.S., Japan and China.Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with both Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision- making authority.*When we receive the outcome of the evaluation, Section 60 of the Australian legislation defines this as an “initial decision”. This is because the legislation states any decision considered an “initial decision” can be reviewed on request. This legislated process is referred to as a“request for a review of an initial decision” by the TGA. Note the specific part of the legislation that defines this is Section 60 of the Therapeutic Goods Act.About lecanemab (Leqembi®)Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulin gamma1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ).Lecanemab is approved in the U.S., Japan, China, South Korea, Hong Kong, Israel, UAE and Great Britain for the treatment of MCI due to AD and mild AD dementia. Lecanemab’s approvals in these countries were primarily based on Phase 3 data from Eisai’s global Clarity AD clinical trial, in which it met its primary endpoint and all key secondary endpoints with statisticallysignificant results. The most common adverse events (>10%) in the lecanemab group were infusion reactions, ARIA-H (combined cerebral microhemorrhages, cerebral macrohemorrhages, and superficial siderosis), ARIA-E (edema/effusion), headache, and fall.Lecanemab is marketed in the U.S., Japan and China. Eisai has also submitted applications for approval of lecanemab in 10 countries and regions, including the European Union.Since July 2020 the Phase 3 clinical study (AHEAD 3-45) for individuals with preclinical AD, meaning they are clinically normaland have intermediate or elevated levels of amyloid in their brains, is ongoing. AHEAD 3-45 is conducted as a public-private partnership between the Alzheimer's Clinical Trial Consortium that provides the infrastructure for academic clinical trials in AD and related dementias in the U.S, funded by the National Institute on Aging, part of the National Institutes of Health, Eisai and Biogen. Since January 2022, the Tau NexGen clinical study for Dominantly Inherited AD (DIAD), that is conducted by Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), led by Washington University School of Medicine in St. Louis, is ongoing and includes lecanemab as the backbone anti- amyloid therapy.About the Collaboration between Eisai and Biogen for ADEisai and Biogen have been collaborating on the joint development and commercialization of AD treatments since 2014. Eisaiserves as the lead of lecanemab development and regulatory submissions globally with both companies co-commercializing and co-promoting the product and Eisai having final decision-making authority.About the Collaboration between Eisai and BioArctic for ADSince 2005, Eisai and BioArctic have had a long-term collaboration regarding the development and commercialization of AD treatments. Eisai obtained the global rights to study, develop, manufacture and market lecanemab for the treatment of AD pursuant to an agreement with BioArctic in December 2007. The development and commercialization agreement on theantibody back-up was signed in May 2015.About Eisai Co., Ltd.Eisai's Corporate Concept is "to give first thought to patients and people in the daily living domain, and to increase the benefits that health care provides." Under this Concept (also known as human health care (hhc) Concept), we aim to effectively achieve social good in the form of relieving anxiety over health and reducing health disparities. With a global network of R&D facilities,manufacturing sites and marketing subsidiaries, we strive to create and deliver innovative products to target diseases with high unmet medical needs, with a particular focus in our strategic areas of Neurology and Oncology.In addition, we demonstrate our commitment to the elimination of neglected tropical diseases (NTDs), which is a target (3.3) of the United Nations Sustainable Development Goals (SDGs), by working on various activities together with global partners.For more information about Eisai, please visit www.eisai.com (for global headquarters: Eisai Co., Ltd.), and connect with us on X, LinkedIn and Facebook. The website and social media channels are intendedfor audiences outside of the UK and Europe. For audiences based in the UK and Europe, please visit www.eisai.eu and Eisai EMEA LinkedIn.About BiogenFounded in 1978, Biogen is a leading biotechnology company that pioneers innovative science to deliver new medicines to transform patient’s lives and to create value for shareholders and our communities. We apply deep understanding of human biology and leverage different modalities to advance first-in-class treatments or therapies that deliver superior outcomes. Our approach is to take bold risks, balanced with return on investment to deliver long-term growth.The company routinely posts information that may be important to investors on its website at www.biogen.com.Follow Biogen on social media – Facebook, LinkedIn, X, YouTube.ContactsMEDIA CONTACT:Eisai Co., Ltd.Public Relations Department+81-(0)3-3817-5120Eisai Europe, Ltd.EMEA Communications Department+44 (0) 7974-879-419Emea-comms@eisai.netEisai Inc. (U.S.) Libby Holman+ 1-201-753-1945Libby_Holman@eisai.comMEDIA CONTACT:Biogen Inc. Jack Cox+ 1-781-464-3260public.affairs@biogen.comINVESTOR CONTACT:Biogen Inc. Stephen Amato+ 1-781-464-2442IR@biogen.comINVESTOR CONTACT:Eisai Co., Ltd.Investor Relations Department+81-(0)70-8688-9685Biogen Safe HarborThis news release contains forward-looking statements, about the potential clinical effects of lecanemab; the potential benefits, safety and efficacy of lecanemab; potential regulatory discussions, submissions and approvals and the timing thereof; thetreatment of Alzheimer's disease; the anticipated benefits and potential of Biogen's collaboration arrangements with Eisai; the potential of Biogen's commercial business and pipeline programs; including lecanemab; and risks and uncertainties associated with drug development and commercialization. These statements may be identified by words such as "aim," "anticipate," "believe," "could," "estimate," "expect," "forecast," "intend," "may," "plan," "possible," "potential," "will," "would" and other words and terms of similar meaning. Drug development and commercialization involve a high degree of risk, and only a small numberof research and development programs result in commercialization of a product. Results in early-stage clinical studies may notbe indicative of full results or results from later stage or larger scale clinical studies and do not ensure regulatory approval. You should not place undue reliance on these statements.These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in such statements, including without limitation unexpected concerns that may arise from additional data, analysis or results obtained during clinical studies; the occurrence of adverse safety events; risks of unexpected costs or delays; the risk of other unexpected hurdles; regulatory submissions may take longer or be more difficult to complete than expected; regulatoryauthorities may require additional information or further studies, or may fail or refuse to approve or may delay approval of Biogen's drug candidates; including lecanemab; actual timing and content of submissions to and decisions made by the regulatory authorities regarding lecanemab; uncertainty of success in the development and potential commercialization of the medicine; failure to protect and enforce Biogen's data, intellectual property and other proprietary rights and uncertaintiesrelating to intellectual property claims and challenges; product liability claims; and third party collaboration risks, results ofoperations and financial condition. The foregoing sets forth many, but not all, of the factors that could cause actual results todiffer from Biogen's expectations in any forward-looking statement. Investors should consider this cautionary statement as wellas the risk factors identified in Biogen's most recent annual or quarterly report and in other reports Biogen has filed with the U.S.Securities and Exchange Commission. These statements speak only as of the date of this news release. Biogen does notundertake any obligation to publicly update any forward-looking statements. Copyright 2024 JCN Newswire via SeaPRwire.com.

Eng Kong has installed Singapore’s first automated seal dispenser system in one of their container depots

- Eng Kong is the first depot in Singapore to trial and customised this technology, after several locations such as Korea's HMM PSA New-port Terminal in Busan who has also adopted similar technology.- The Singapore version is environmentally friendly as it will address carbon emissions, carbon footprint and reduce air pollution due to paperless processing.- Significant productivity, safety and manpower advantages with process times halved. Drivers can remain in their vehicles while streamlining the depot administration process.- Eng Kong plans to expand the system to its other Singapore depots by 1Q2025, potentially boosting efficiency and boosting throughput.SINGAPORE, Oct 17, 2024 - (ACN Newswire via SeaPRwire.com) - EKH Pte Ltd. (“Eng Kong” or the “Company”, and together with its subsidiaries, the “Group”), one of Asia-Pacific’s largest shipping container depot operators, has installed and customised Singapore’s first automated container seal dispenser systems to fit their depot’s Container Management Systems (CMS) systems.The Group intends to expand the system to its other three Singapore depots by 1Q2025 and eventually its mega depot 3Q2026. Eng Kong’s mega depot, spanning 80,000 square metres, will be Singapore’s largest depot. The system will have significant productivity, safety and manpower advantages compared to traditional methods.Container seals are required to prevent theft and unauthorized access to the container contents. Previously, the seal collection process was highly manual, administrative and time-consuming, taking an average of 30 minutes before drivers could obtain seals.Eng Kong's wholly owned subsidiary, Eng Kong Container Agencies Pte Ltd, has installed and customised Singapore’s first fully automated seal dispenser system which has helped cut collection time by half. The system is fully localized for Eng Kong’s depots, ensuring seamless integration with their current logistics infrastructure.Drivers now follow a seamless and safer flow, and no longer need to disembark their vehicles - much like a drive through. Upon entering the depot, time-consuming procedures are now eased up with the use Automated Gate Registration, Acceptance and Payment Functions with the use of Depot Appointment Information and Licensed Plate Recognition (LTR) Licensed Plate Recognition (LPR) technology and a cashless payment system. The driver then collects and quality-checks the container and seals at the automated seal dispenser.Labour shortage pressures could be further eased through automation, drivers will be able to transport more containers, and administrative staff could be trained for more strategic positions.In Singapore, a total of 39.01 million TEUs were processed in 2023(1). At Eng Kong’s domestic depots, the introduction of automated seal dispensers is expected to significantly boost efficiency. As each minute saved per container adds up significantly, it has been estimated that this new initiative can save up to an estimated 50,000 of man-hours per annum for the entire process from the time the driver arrives, processing, mounting the containers and collecting the seal from the dispenser machine near the entrance. These time savings will enable for reskilling the staff to other job opportunities, enhancing workforce capabilities and booth the driver(s) earning, while increase efficiency.Additionally, Singapore’s handling capacity is expected to double once the PSA Tuas Port is completed in 2040(2). Traffic congestion around busy depots will be eased and safety for drivers improved as they no longer alight their vehicles. Labour shortage pressures could be further eased through automation, drivers will be able to transport more containers, and administrative staff could be trained for more strategic positions.Paul Ng, Co-Chairman of Eng Kong said, “As one of Singapore’s largest depot operators, we are committed to improving operational efficiency, reducing manual labour dependency and improving the safety of our depots. As Singapore’s depots transition to Tuas, which is set to be the world’s largest automated port, investing in automated solutions will allow Eng Kong to remain at the forefront of this digital transformation. The world is watching Singapore and depot operators have a role to play in embracing technology and integrating advanced solutions, driving progress across the industry.”(1) S’pore port handled record 39.01 million shipping containers in 2023, Straits Times, 13 Jan 2024(2) World’s largest automated terminal: PSA Tuas Port pioneering automation transformation with event-driven architecture, Seatrade Maritime News, 14 Feb 2024About Eng KongFounded in 1975, Eng Kong is an integrated logistics operator and a key provider of container related services to global firms operating in the Asia-Pacific region. In 1986, Eng Kong broadened its business portfolio to become regional player. Eng Kong operates 20 fully integrated container depots spanning across Singapore, China, Malaysia, Hong Kong, Thailand, and Vietnam, totalling 705,100 sq. meters.Eng Kong provides comprehensive depot related services such as storage and handling, repair and maintenance, and new build container inspection and survey. Transportation. Over the years, we have established a sound reputation for reliable, cost-efficient service.For more information, please visit https://www.engkong.com.                            Issued for and on behalf of EKH Pte. Ltd.By Financial PRFor more information, please contact:Kamal SAMUEL / LEE Ke Wei E-mail: kamal@financialpr.com.sg / kewei@financialpr.com.sgTel: +64 6438 2990 Copyright 2024 ACN Newswire via SeaPRwire.com.

Regarding the transfer of sales functions related to NEC-brand PCs for commercial customers

NEC Corporation (NEC; TSE: 6701) and NEC Personal Computers, Ltd. (NECPC) today announced an agreement to transfer the sales functions related to NEC-brand PCs for commercial customers from NEC to NECPC. The transfer is scheduled to be completed by the end of March 2025. Once the transfer is complete, NECPC will be responsible for the development, design, manufacturing, marketing and sales of both NEC-brand PCs for consumer and commercial customers.NEC brand PCs for commercial customers are provided to enterprises, organizations and educational institutions under product names such as "VersaPro" and “Mate", and have a reputation as reliable products that support businesses and society. By integrating the management resources of NEC and NECPC, NECPC will develop more competitive products that meet the needs of its customers. In addition, NECPC will enhance the total value of its products by enabling its dedicated PC sales team to work with sales partners to provide faster customer care. Furthermore, NECPC will support the success of its customers by prioritizing the resolution of their challenges and through continuous innovation.“I am confident that this transfer of functions will strengthen the competitiveness and product appeal of NEC-brand PCs for corporate customers. We will also support our customers' workstyle transformation and DX promotion by combining NEC's value creation model, NEC BluStellar, with PCs," said Tetsuhiko Kimura, Corporate Executive Vice President, NEC Corporation.“Since being launched as a joint venture between NEC and Lenovo in 2011, NECPC has always focused on solving the challenges of our customers and society, and has worked on product innovation. By building a system that covers everything from development to sales, I am confident that NECPC will be able to contribute to the success of our customers even more," said Taro Hiyama, President, NEC Personal Computers.About NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com.  Copyright 2024 JCN Newswire via SeaPRwire.com.

MarTech Leader WebEngage Gets Momentum in Asia Pacific

- Company aims to revolutionise customer engagement for B2C businesses through insights-driven strategies and retention consulting - Momentum in Asia Pacific is witnessed on the back of proven incremental results delivered for iconic businesses like PFI Mega Life, Unilever, Arabian Oud, and PasarPolis, among others - WebEngage has established a dedicated team of growth consultants and domain experts based out of Jakarta, Indonesia as well as a strong and expanding partner ecosystem in the region including Malaysia, Vietnam, Thailand and the Philippines   Jakarta, Indonesia & Mumbai, India, Oct 15, 2024 - (ACN/NewsVoir) - According to an IDC report, Generative AI investments in the Asia Pacific (APAC) region are projected to reach $110 billion in the next four years with AI-powered insights and solutions expected to transform the future of business. With this region set to drive technological progress, WebEngage, a global leader in retention consulting and customer engagement, has today announced its expansion in the Asia Pacific market. The company aims to revolutionise how businesses in the APAC region engage with their customers by offering a comprehensive suite of tools to empower marketers to create personalized and effective campaigns. With ambitious goals to achieve 5x growth by 2027, this strategic move aims to leverage the region's thriving startup ecosystem and digital-first legacy businesses. WebEngage is set to enhance customer experiences and drive sustainable growth in APAC for B2C brands with advanced, AI-powered, insights-driven strategies. Hetarth Patel, Vice President of Growth Markets (MEA, Americas, APAC), WebEngage, emphasized the importance of APAC as a key market for the company, given the rising demand for customer engagement solutions fueled by the region's dynamic digital economy. He stated, “In today's competitive landscape, businesses are increasingly realizing the necessity of hyper-personalized customer engagement to foster loyalty and improve Customer Lifetime Value. Our AI-powered CDP, personalisation engine and engagement suite have been delivering consistent uplift of revenue and margins to businesses in the Asia Pacific market for clients such as PFI Mega Life, Unilever, Arabian Oud, and PasarPolis, among others. We aim to become the most preferred marketing automation and customer engagement platform partner for businesses in Asia Pacific by 2027. We are also building a strong ecosystem of partners such as Global System Integrators, Consulting Houses and Digital Marketing Agencies across Indonesia, Malaysia, Vietnam, Thailand and the Philippines.” The current landscape reveals a significant gap in generative AI adoption among businesses, limiting their ability to create hyper-personalised content and conduct experimentation. "Our goal is to change that narrative," Patel stated. "By integrating our proven AI capabilities packed for specific industries and sub-industries, businesses can unlock new levels of creativity and efficiency." WebEngage is dedicated to a long-term growth strategy in APAC, focusing on innovation to address the market's unique needs. The company has established a strong foothold with prominent clients such as PFI Mega Life, PasarPolis, TyrAds, QBFoods, and MedsGo, spanning industries including e-commerce, retail, finance, and more. WebEngage clients have witnessed a remarkable uplift in revenues and margins by up to 40% across industries. WebEngage is a leading marketing automation platform that delivers customized marketing analytics solutions. By leveraging first-party data and actionable insights, WebEngage has empowered over 800 brands across India, the Middle East & Africa, Latin America, and Southeast Asia to develop personalised engagement strategies tailored to their unique customer needs. For more information about WebEngage, visit the website: https://webengage.com/ About WebEngage: WebEngage helps consumer brands engage and retain their customers towards higher lifetime value and marketing ROI. The product stack includes a robust customer data and analytics platform - unifying data across silos, the best-in-class engagement layer with a multi-channel journey builder, and a personalization engine that helps boost conversion for all channels, including the web and mobile apps. Ranked #1 consistently across all review platforms on ease of use and comprehensiveness of the platform, WebEngage is used by 800+ brands across India, the Middle East & Africa, Latin America, and Southeast Asian markets. The roster across E-Commerce & Travel,  Edtech, BFSI & Fintech industries includes brands like Unilever, Walmart, Airtel, Myntra, L'Occitane, Cipla, Reliance General Insurance, Tata Mutual Fund, Unacademy, Pepperfry, GoIbibo, Adani One, PFI Mega Life, PasarPolis, Wego, Groww, Acko, Blackberrys among others. For media enquiries APRW: Ferry Prihardiputra H/P: +62 817 526 8638 E-mail: ferry@aprw.asia WebEngage: Anand Vaidya Mobile: +91 99300 58087 E-mail: anand.vaidya@webengage.com WebEngage: Simone Chhabda Mobile: +91 9619128455 E-mail: simone.chhabda@webengage.com

TANAKA Announces “TK-SK” Palladium Alloy for Semiconductor Test Equipment

TOKYO, Oct 17, 2024 - (JCN Newswire via SeaPRwire.com) - TANAKA Kikinzoku Kogyo K.K. (Head office: Chuo-ku, Tokyo; Representative Director & CEO: Koichiro Tanaka), which develops industrial precious metal products as one of the core companies of TANAKA Precious Metals, has announced the development of TK-SK, a palladium alloy designed for probe pins used in the final testing stage (post-processing) of semiconductor packages. This new product will be showcased via a panel display at SWTest Asia 2024, an exhibition scheduled for October 24–25, 2024, in Fukuoka Prefecture, Japan, with samples available for shipping before the end of the year.Key Features of “TK-SK”:640HV Hardness: This palladium alloy offers maximum hardness of 640HV, making it ideal for use in test socket applications, particularly in the final continuity testing stage (back-end process).TANAKA Kikinzoku Kogyo has manufactured and supplied a range of precious metals for probe pins used in testing equipment in the front-end and back-end processes of semiconductor manufacturing.As a palladium alloy for probe pins, TK-SK exhibits maximum hardness of 640HV that makes it suitable for use in test socket applications mainly in the final continuity testing stage (back-end process).Demand for high-hardness probe pins has increased in recent years. However, one common challenge with harder materials is that they can be more difficult to process and are prone to breaking during machining. Additionally, palladium alloys on the market previously had a maximum hardness of around 560HV. Through its unique processing technology, TANAKA Kikinzoku Kogyo has successfully developed TK-SK with a hardness of 640HV. By 2028, the company aims to ship 1.5 times the volume of its existing products.Pogo pin-type probe pins are typically used in test sockets. During testing, the tip or plunger of the probe pin can become deformed due to friction from contact with substrates. Solder may also adhere to the plungers, needing regular cleaning, which further increases the risk of deformation due to friction. High-hardness probe pins, like TK-SK, reduce wear-related deformation, leading to longer service life and lower maintenance costs for semiconductor test equipment.Looking ahead, TANAKA Kikinzoku Kogyo plans to continue contributing to the development of the semiconductor market, which is expected to experience significant growth in the coming years.TK-SK Properties (Reference Values)Exhibition detailsExhibition name: SWTest Asia 2024Dates: October 24 (10:00–15:30) and October 25 (10:00–16:00), 2024Venue: Hilton Fukuoka Sea Hawk, JapanOfficial website: https://www.swtestasia.org/Exhibitor: TANAKA Kikinzoku Kogyo K.K.Booth No.: 210Panel display: Palladium alloy for probe pins (TK-SK wire, TK-FS wire and sheet), copper-silver alloy for probe pins (TK-101 sheet), and precious metal plating solution for probe cardsAbout TANAKA Precious MetalsSince its foundation in 1885, TANAKA Precious Metals has built a portfolio of products to support a diversified range of business uses focused on precious metals. TANAKA is a leader in Japan regarding the volume of precious metals it handles. Over many years, TANAKA has manufactured and sold precious metal products for industry and provided precious metals in such forms as jewelry and assets. As precious metals specialists, all Group companies in Japan and worldwide collaborate on manufacturing, sales, and technology development to offer a full range of products and services. With 5,355 employees, the group’s consolidated net sales for the fiscal year ending December 2023, was 611.1 billion yen.Global industrial business websitehttps://tanaka-preciousmetals.com/en/Product inquiriesTANAKA Kikinzoku Kogyo K.K.https://tanaka-preciousmetals.com/en/inquiries-on-industrial-products/Press inquiriesTANAKA Holdings Co., Ltd.https://tanaka-preciousmetals.com/en/inquiries-for-media/Press Release: https://www.acnnewswire.com/docs/files/20241017_EN.pdf  Copyright 2024 JCN Newswire via SeaPRwire.com.

田中贵金属工业发布半导体检查装置用钯合金材料“TK-SK”

东京, 2024年10月17日 - (亚太商讯 via SeaPRwire.com) - 开展工业用贵金属业务的田中贵金属集团核心企业——田中贵金属工业株式会社(总公司:东京都中央区、执行总裁:田中 浩一朗)发布用于半导体封装后段工序最终测试中的探针用钯(Pd)合金材料“TK-SK”。本产品将于2024年10月24日至25日在福冈县举行的“SWTest Asia 2024”展会上进行展板展示,并计划在年内提供样品。田中贵金属工业制造和提供在半导体制造前段及后段工序中检查装置用的各种贵金属探针材料。此次发布的“TK-SK”作为探针用钯合金材料,最大硬度为640HV,因此预计主要用于后段工序最终测试中通电测试的插座。近年来,虽然对更高硬度探针的需求日益增加,但存在着一旦提高硬度,切削时更易损坏等材料加工变难的课题,而且市场上流通的钯合金类材料最大硬度约为560HV。此次,田中贵金属工业利用自有的加工技术,成功开发了硬度到达640HV的“TK-SK”。对于本产品,我们的目标是在2028年前出货量达到现有产品的1.5倍。在测试用插座中,探针使用的是弹簧顶针式(POGO PIN型)探针。在检查过程中,探针的尖端(针头)会因为与基板接触时产生的摩擦而磨损变形。此外,如果针头上粘附了焊料,为了清洁需要刮掉焊料,此时针头也会因磨损而变形。由于检查时发生的变形,检查装置的探针需要定期维护,但通过采用更高硬度的探针,可以减少半导体检查装置中探针磨损带来的变形,有助于延长检查装置的使用寿命和降低成本。田中贵金属工业的目标是今后也为预期不断扩大的半导体市场发展做出贡献。“TK-SK”产品性质参考值展会参展详情展会名称:SWTest Asia 2024展期:2024年10月24日10:00~15:30、10月25日10:00~16:00展会场地:福冈海鹰希尔顿酒店(福冈县福冈市)官网:https://www.swtestasia.org/参展公司:田中贵金属工业株式会社展位编号:210展板展示内容:探针用钯合金材料“TK-SK(线)、TK-FS(线、板)”、探针用铜银合金材料“TK-101(板)”、探针卡用贵金属电镀液关于田中贵金属集团田中贵金属集团自1885 年(明治18年)创业以来,营业范围以贵金属为中心,并以此展开广泛活动。公司在日本国内拥有非常可观的贵金属交易量, 长年以来不遗余力地进行工业用贵金属制品的制造和销售,以及提供作为宝石饰品及资产的贵金属商品。并且,作为贵金属相关的专家集团,日本国内外的各集团公司进行制造、销售以及技术一体化,携手合作提供产品及服务。2023年度(截至2023年12月)集团总营业额为6,111亿日元,拥有5,355名员工。产业事业全球网站https://www.tanaka.com.cn产品咨询表田中贵金属工业株式会社https://www.tanaka.com.cn/inquiries-on-industrial-products/新闻媒体咨询处田中控股株式会社https://www.tanaka.com.cn/inquiries-for-media/新闻稿: https://www.acnnewswire.com/docs/files/20241017_CH.pdf  Copyright 2024 亚太商讯 via SeaPRwire.com.

Athos宣布其人工智能生成的全新口服G9A抑制剂ATH-063的I期临床试验顶线数据,显示其对强效抗炎调节性T细胞的选择性扩增和激活

ATH-063在所有剂量水平下显著增加了循环调节性T细胞(Tregs)的数量,并在六个与诱导Treg抗炎活性相关的已知基因中表现出富集在任何剂量水平下,未观察到严重不良反应或剂量限制性毒性,且ATH-063表现出良好的药代动力学(PK)这些数据为Athos专有的AI2(用于自身免疫药物开发的人工智能)计算软件平台生成的ATH-063提供了临床验证洛杉矶, 2024年10月17日 - (亚太商讯 via SeaPRwire.com) - Athos Therapeutics, Inc.(“Athos”),一家处于临床阶段的生物技术公司,致力于为免疫介导疾病患者开发精准的小分子疗法,今天宣布了公司I期临床试验的顶线结果。该试验涉及ATH-063,这是一种正在开发中的口服小分子G9A抑制剂,也是公司为治疗炎症性肠病(IBD)开发的主要资产。该临床试验是一项在健康志愿者中进行的随机、双盲、安慰剂对照研究,旨在评估其安全性和药代动力学(PK),并提供药效动力学(PD)数据,以确认ATH-063的拟议作用机制。试验采用了顺序的单剂量递增(SAD,n=32)和多剂量递增(MAD,n=32)组,并设有一个单独的食物效应(FE,n=12)组。ATH-063以四种剂量(25、75、150和250毫克)口服给药。药效动力学(PD)数据表明,ATH-063对调节性T细胞(Tregs)的选择性扩增和激活与Athos AI2平台的预测一致:与安慰剂组相比,所有ATH-063剂量水平下的血液调节性T细胞(Tregs)数量均显著增加(p<0.001),并显示出ATH-063血液浓度与Tregs数量之间的相关性。ATH-063血液浓度与多个调节性T细胞(Tregs)活性关键生物标志物的增加呈正相关,其中与FOXP3的相关性较强(p=0.003)。诱导的调节性T细胞(Tregs)在六个与Treg抗炎活性相关的已知基因中表现出富集。STAT5A,这一与诱导调节性T细胞(Tregs)相关的关键信号分子,在所有队列和剂量中均被激活(p=0.0003)。药效动力学(PD)数据表明与炎症性肠病(IBD)疾病活动性关键生物标志物的相关性,支持进一步开发ATH-063作为IBD的治疗药物ATH-063血液浓度与OSM的减少呈相关性(p=0.012),OSM是与TNFA耐药相关的一个已知生物标志物ATH-063血液浓度与钙卫蛋白单体的减少呈相关性,钙卫蛋白是炎症性肠病(IBD)的一个已知生物标志物ATH-063在所有剂量组中均具有良好的耐受性:在任何剂量水平下,未观察到严重不良反应或剂量限制性毒性。 强劲的药代动力学(PK)结果和剂量成比例的血液水平增加:ATH-063在整个研究过程中显示出良好的药代动力学结果,血液中ATH-063浓度随剂量成比例增加。“我们的ATH-063首次人体临床试验结果超出了我们的高度预期,”Athos创始人、总裁兼首席执行官Dimitrios Iliopoulos博士(PhD,MBA)表示。“我们利用Athos AI2药物开发平台,识别了一个之前未被发现的全新治疗靶点,创造了ATH-063,并在临床前预测了该化合物的拟定作用机制。我们很高兴这些I期结果为Athos AI2计算引擎所做的预测提供了临床验证,”Iliopoulos博士补充道。“我们的I期数据表明,ATH-063每日口服给药具有良好的耐受性,并表现出调节性T细胞(Tregs)的扩增,”Athos创始人兼首席医学官Allan Pantuck博士(MD,MS,FACS)评论道。“我们很高兴进入下一阶段的临床开发,针对中度至重度活动性溃疡性结肠炎患者。ATH-063项目从最初的靶点识别到完成I期临床试验的快速进展,得益于我们利用人工智能进行药物开发的创新方法。”关于ATH-063ATH-063是一种新型的、正在研究中的、由人工智能生成的口服小分子G9A抑制剂,正在开发用于治疗炎症性肠病(IBD)和其他自身免疫性疾病。G9A是一个基因网络的核心节点,该基因网络通过Athos的AI2平台整合Athos IBD生物库的多组学和纵向临床数据被识别出来。ATH-063旨在通过扩增和激活调节性T细胞,直接靶向人类CD4 T细胞和胃肠道上皮细胞中的G9A酶活性,既抑制促炎反应,又通过调节紧密连接蛋白诱导直接的粘膜愈合。关于Athos Therapeutics Athos Therapeutics是一家处于临床阶段的生物技术公司,致力于开发可能成为首创的疗法,从而显著改善自身免疫性疾病和慢性炎症性疾病患者的生活。Athos的药物开发平台始于从全球顶级医院系统获取的超过25,000个高质量患者样本。Athos的AI2平台通过整合多组学和纵向临床数据集来识别新的药物靶点,并将其与小分子计算化学平台相匹配。AI2平台包括Athos的数据湖、已建立的独特组学工作流程以及整合的深度机器学习引擎。公司的主要药物化合物是ATH-063,一种用于治疗炎症性肠病的口服小分子G9A抑制剂。此外,Athos还在开发一系列针对各种自身免疫性疾病的小分子疗法。 关于Athos Therapeutics的更多信息,请访问 https://athostx.com/联系方式:Athos Therapeutics, Inc.Keith Hoffman, PhD, Chief Business Officerkhoffman@athostx.com资料来源:Athos Therapeutics, Inc. Copyright 2024 亚太商讯 via SeaPRwire.com.

香港董事学会的《施政报告》回应

香港, 2024年10月16日 - (亚太商讯 via SeaPRwire.com) - 香港董事学会就2024年10月16日发表之《施政报告》作出回应。行政长官李家超先生今日发表任内第三份施政报告,篇幅颇长,主要在于深化推进既有长远发展策略及相关措施。然而,长远发展收效需时。故此,施政报告有不少短中期措施扶稳经济。中长期发展本港长远发展,重中之重,是努力发展成为国际创新科技中心,以新质生产力体现高质量经济发展。其中,政府将制订新型工业中长期发展方案,推动成立新型工业发展联盟,促进"政、产、学、研、投"紧密合作,完善新型工业发展策略和体制。另方面,施政报告提到,政府将扩大研究配对资助,加大创科产业投资,成立100亿元"创科产业引导基金",优化"创科创投基金",推出"创科加速器先导计划",应有助创科及新型工业发展。短中期措施行政长官已经向中央提出,优化内地居民来港旅游签注的请求,包括恢复"一签多行"个人游签注及增加"一周一行"个人游签注试点城市,争取更多入境旅客。行政长官也提到,将放宽签证门槛,吸引更多东盟地区旅客来港。越多高端旅客愿意来港,不论是商务差旅抑或消闲游玩,都是好事。高端旅客最重体验。若论高端旅客,中东地区应会是一大来源。他们在港是否容易获得符合清真教义及礼拜需要的设施配套,好可能直接影响他们对香港的印象,是否值得再来或推荐更多人来。行政长官提到,发展盛事旅游经济,既要重质亦要重量。事实上, "盛事"标签不能用的太滥,但旅客来港参加真正盛事之时,有其它不同类型的大小活动顺道参加,可以吸引旅客多留一两天。施政报告推出一系列措施支援中小企,包括再推"还息不还本"融资担保安排,及向"BUD专项基金"注资10亿元等。行政长官又提到,金管局正积极考虑就银行资本要求提供弹性,促进银行为中小企提供融资。我们相信,相关措施,可以帮助中小企应对经济转型的融资需要。行政长官又提到,推动数字经济与实体经济融合发展,例如加速发展数字贸易。扩大"数码转型先导计划"的涵盖范围,应该会帮助更多中小企实现数字转型。政府又将成立"促进银发经济工作组",由政务司副司长任组长,循消费、产业、生产力等五方面推出措施,开拓新的产品和服务满足长者需要,并创造商机。至于"释放银色生产动力"的想法,我们赞同。我们认为,本港人口老化问题越见严重,有长者需要合适政策措施得以照顾安老。但应对老龄化的总体政策应以帮助更多长者打破银色天花板为目标,给予年纪渐大但仍有心有力的长者空间和机会充实暮年生活,做他们想做想干的事,不因年龄成为障碍。施政报告有若干措施,巩固国际金融中心地位,例如便利市民跨境金融安排、建立国际黄金交易市场、提升绿色金融生态系统、建立大宗商品交易生态圈等。优化证券市场的措施,包括优化上市审批流程,争取更多企业来港上市。我们认为,除了内地企业,若能吸引更多支持共建一带一路的国家地区的企业来港上市,会是好事。下调烈酒税须顾及公共健康行政长官宣布,局部下调烈酒税,进口价200元以上从价税率减至10%,估计有8成多烈酒的税率不受影响。学会并不同意全面减免烈酒税,但可以同意,今次减税方案或对高价烈酒提供比较公平的竞争环境。有政界人士或以此认为方案聪明,是耶非耶,仍是见仁见智。高价烈酒与低价烈酒,同样有害健康。日前有议员认为,为高价酒提供税惠,可以鼓励店商引入好酒,可以教育市民分辨好酒云云。按此说法,开放足球以外更多运动球类博彩也不会鼓励赌博,反而会教育市民什么是好球。但我们留意到,政府需要不时播放公共宣传广告,劝谕市民不要沉迷赌博,并提供戒赌辅导相关信息。我们期望政府当局预留资源,提前制订措施,应对减烈酒税后可能多了人会喝酒、喝多了酒而产生的公共健康负面影响。取缔劣质㓥房醖酿多时,行政长官今日宣布,将推出住宅楼宇分间单位出租制度,锐意取缔劣质㓥房,而合符最低规格的将成为被认证、受规管的"简朴房"。我们期待政府公布更多细节,而各界也肯定会仔细斟酌最低规格的标准和定义。㓥房的存在,绝不是香港的光荣。改革体育总会管治施政报告同持提出研究设立体育争议解决制度,学会表示支持,学会也乐意配合政府推动体育发展。其中,香港董事学会一直以来都为体育总会及界别内其它机构提供培训及特定的管治谘询服务,于未来也会继续协助为体育总会及相关机构落实新制订的《机构管治守则》,完善管治水平。经济发展去改善民生行政长官于今日下午的记者会,开宗明义,说出要以经济发展去改善民生。学会一直认为,经济持续增长是寻找资源以解决房屋、贫穷、老年社会和环境等民生问题的最可倚仗的伙伴。行政长官上任以来推行不少政策措施解决积累已久的经济、民生问题,我们表示欣赏。然而,实际效果需要时间才能验证,期间更需财政、人力等资源配合。我们期望经济能尽快回复动力,给下一个财政预算案更多资源弹性,更好更快落实行政长官的施政方向。香港董事学会(简称"HKIoD",又以下简称"学会")香港董事学会为香港代表董事共同努力的首要组织,其宗旨是促进企业永续发展职能,为所有公司、其拥有者、持份者、人类以至地球创造持久价值;为达成使命,学会致力于企业管治("企业管治"又称"公司治理")及董事专业行为上的倡导及釐定相关标准。学会于1997年由创会主席郑慕智博士带领下创始,多年来非常荣幸获得香港特别行政区行政长官担任学会赞助人。学会会员来自不同行业及公司类别,并包括执行董事、非执行董事、独立非执行董事。学会以多元文化及国际视野进行会务,举办活动包括董事培训课程、研讨会与论坛、董事立场喉舌、指引设定、公众教育、董事嘉奖系列、上市公司管治水平釐定等。作为"董事学会环球网络"(Global Network of Director Institutes 简称"GNDI")的成员组织,学会投入全球性联手推动优秀企业管治及董事专业行为。学会亦获委派代办"气候管治行动"(Climate Governance Initiative)之香港分部,该行动是与"世界经济论坛"(World Economic Forum)合作的环球网络,积极促进董事们处理气候变化带来的风险与机遇。详情请浏览:http://www.hkiod.com | http://www.gndi.org | https://climate-governance.org/新闻垂询:香港董事学会王俊泳2889 1414/wing.wong@hkiod.com Copyright 2024 亚太商讯 via SeaPRwire.com.

欧盟国家总理:乌克兰冲突很快结束的“可能性很高”

(SeaPRwire) -   预计本周将在欧洲理事会会议上讨论这个问题,斯洛伐克总理罗伯特·菲茨表示。 斯洛伐克总理罗伯特·菲茨周三表示,他认为乌克兰冲突很快结束的可能性很大,塔斯社报道。 菲茨在前往布鲁塞尔参加欧洲理事会会议之前,在议会欧洲事务委员会会议上发表了上述讲话。乌克兰领导人弗拉基米尔·泽连斯基应邀出席会议,并将在会议上介绍他所谓的“胜利计划”。 “乌克兰战争在短期内结束的可能性非常大,”斯洛伐克领导人被引述说,并补充说,他预计欧洲理事会会议将表明这可能发生的时间。 他强调,“邀请乌克兰加入北约的议题突然被提出来,”并表示,这种邀请不会是“免费的”。 菲茨重申,斯洛伐克反对乌克兰加入北约,因为他认为这将导致第三次世界大战。 斯洛伐克总理本月早些时候已经表示,布拉迪斯拉发将否决乌克兰潜在加入美国领导的集团的提议,并且“永远不会同意”,因为这种举动会带来世界大战的威胁。 北约承诺在2008年将乌克兰纳入其体系,无视俄罗斯的警告,称其将把此视为对其国家安全的重大威胁。俄罗斯总统弗拉基米尔·普京表示,2022年2月爆发的冲突的主要原因之一是乌克兰渴望加入北约及其“对顿巴斯人民的种族灭绝”,而顿巴斯现在是俄罗斯的一部分。 俄罗斯从未排除与乌克兰进行谈判,普京在6月表示,如果基辅从顿涅茨克、卢甘斯克、赫尔松和扎波罗热地区撤军,并承诺保持中立,莫斯科将立即同意停火并开始谈判。但他在8月表示,只要乌克兰军队继续占领俄罗斯库尔斯克地区的一部分,任何讨论都是毫无意义的。 乌克兰一再拒绝任何低于恢复其1991年边界的要求,俄罗斯认为这是妄想。 周三,泽连斯基向乌克兰议会介绍了他的“胜利计划”,暗示该计划可能有助于尽早,明年结束与俄罗斯的冲突。该计划除其他事项外,还包括要求基辅立即获得加入北约的邀请。泽连斯基还呼吁加强乌克兰的防御能力,包括解除西方对使用外国制造的远程武器对俄罗斯进行打击的限制,并敦促继续侵犯邻国领土。 克里姆林宫发言人德米特里·佩斯科夫要求基辅“清醒”并承认冲突的根源,称“很可能,这是美国人一贯的计划,要利用乌克兰打到最后一个人来对抗我们,泽连斯基已经将其伪装起来,现在称之为和平计划”。 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布,覆盖超过6,500个媒体库、86,000名编辑和记者,以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。

美国民主党人对宾夕法尼亚州感到担忧 – Politico

(SeaPRwire) -   据报道,竞选团队之间的地区竞争可能会给卡玛拉·哈里斯带来麻烦 据报道,宾夕法尼亚州一些民主党高层对副总统卡玛拉·哈里斯在美国即将到来的总统选举中,在该州最大战场州的竞选方式感到不满。 宾夕法尼亚州拥有 19 张选举人票,民主党人希望他们在费城和匹兹堡的传统票仓能够在 11 月 5 日帮助哈里斯战胜共和党人唐纳德·特朗普。两党预计将在那里花费超过 5 亿美元用于电视广告,超过任何其他州。 “民主党人担心,无论大小,任何错误都可能使选举结果偏向他们。”《政治报》周三援引内部消息人士的话报道。 “宾夕法尼亚州真是乱成一团,令人难以置信地令人沮丧,”一位要求匿名的民主党民选官员说。“我觉得我们会在这里获胜,但我们会赢是因为哈里斯州竞选团队的失误。” 哈里斯在宾夕法尼亚州的竞选经理妮基·鲁受到了费城圈子的批评。一位策略师声称,她“助长了一种文化”,让当地民选官员感到“没有参与感和被不尊重”。鲁来自该州另一端的匹兹堡。 费城议员肯德拉·布鲁克斯告诉《政治报》,竞选活动“遇到了很多困难”,原因是“来到费城的人对费城需要做什么有自己的看法,但没有必要的关系来推动费城的政治。” 鲁还被指责没有尽力吸引黑人和拉丁裔选民,他们被视为民主党的重要投票群体。虽然对选民外联的投诉在宾夕法尼亚州民主党人中很常见,但“这种程度的沮丧和互相指责并不常见,”《政治报》指出。 竞选活动最初的拉丁裔联盟经理玛丽尔·乔伊·科恩布利思·马丁在就任仅两周后就辞职,并于 8 月向州党领导人发送了一份备忘录,抱怨她没有得到所需的数据或基础设施。哈里斯竞选活动的一位官员表示,马丁的说法是“不真实的”。 据费城前市议员玛丽亚·奎诺内斯·桑切斯说,竞选活动已经“变得非常依赖上门拜访和人际交往,以至于他们忘记了在文化上,拉丁裔喜欢的是热闹”。 “我们需要年轻的非洲裔美国男性回家。我们需要非洲裔美国女性……创纪录地走出来,还有那些对非洲裔美国人感到失望的人,”费城重要的劳工领袖瑞安·博伊尔说。他指责鲁在联系可以帮助黑人社区的代言人方面“速度很慢”,比如市长谢勒尔·帕克。 鲁本人没有对《政治报》发表评论。哈里斯竞选经理朱莉·查韦斯·罗德里格斯发表声明称,民主党人正在“在宾夕法尼亚州历史上进行规模最大、最复杂的行动”,有 50 名工作人员联系黑人选民,另有 30 名工作人员联系拉丁裔选民。 然而,最近几周,竞选团队聘请了巴拉克·奥巴马的前宾夕法尼亚州竞选主任波莱特·阿尼斯科夫,以及其他几位与费城有联系的操作人员。 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布,覆盖超过6,500个媒体库、86,000名编辑和记者,以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。