ACN Newswire

How to Choose the Right Savings Account for Your Money Goals in Singapore

27 3 月, 2026

SINGAPORE, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) - Choosing where to place your savings in Singapore is an important financial decision that requires careful consideration. With many banks offering different types of accounts, it is easy to get confused. However, picking the right one is the first step to reaching your financial goals, whether you are saving for a dream wedding, a new home, or a retirement fund.The good news is that you no longer need to spend a whole afternoon waiting at a bank branch. You can now open a bank account online in just a few minutes using your phone or computer. Here is a simple guide to help you choose the best account for your needs in 2026.Identify Your Financial HabitsBefore focusing on interest rates, consider how you manage your money on a daily basis. Savings accounts in Singapore usually fall into two categories:The Active Saver: These accounts give you high interest rates, but you have to make a few mandatory transactions each month. Usually, you need to credit your salary and spend a set amount on your credit card.The Passive Saver: These accounts help you earn bonus interest just for keeping your money in the account and letting it grow. You do not need to worry about credit card spending or paying bills.Compare Interest RatesBefore opening a bank account online, make sure you compare the interest rates. Many basic accounts offer low interest rates. To make your money grow, you should look for bonus interest.For example, a high-interest account can offer between 2% and 5% depending on the rules you follow. If you have SGD 50,000, the difference between a basic account and a high-interest one could be hundreds of dollars in extra cash every year. Always check the effective interest rate, which tells you the real amount you will earn after all the levels are counted.Look for Welcome PromotionsBanks in Singapore are always competing for your business. When you open a bank account online, you can often grab a welcome gift, such as cash credits or rewards. These promotions are a great way to get a head start on your savings. Just make sure to check the dates, as many of these flash deals only last for a few months.Check the Fees and MinimumsEven a great account can lose you money if you are not careful about fees. Before you sign up, check for these three things:Minimum balance: Most accounts require maintaining a certain amount of money in the account at all times. If the balance drops below this limit, the bank may charge you a monthly fee.Initial deposit: Some accounts require at least SGD 1,000 to get started.ATM access: Make sure the bank has plenty of ATMs near your home or office so you do not get charged for using the machine of another bank.Open an Account OnlineOnce you have picked the right account, the final step is to fill out your application. In Singapore, you can use Singpass MyInfo to fill out your application automatically.When you open a bank account online, your details, such as your NRIC, address, and income, are pulled directly from the government database, thus reducing paperwork. Most accounts are approved almost instantly, and you can start using your new digital card right away.Final ThoughtsChoosing a savings account is not just about finding the highest interest rate. It is about finding the one that fits how you live. If you are a busy professional who already uses a credit card, an active account is perfect. If you just want to set your money aside and forget it, a passive account is better.By taking 10 minutes to compare your options today, you can ensure that every dollar you earn works as hard as you do.Disclaimer: This article is for general information only and does not have any regard to the specific investment objectives, financial situation and particular needs of any specific person. The views expressed in this article are solely those of the author. This article shall not be regarded as an offer, recommendation, solicitation or advice. You may wish to consult your own professional advisers about this article, in particular, a financial professional before making financial decisions. Any past events, trends and/or performance referred to in this article may not necessarily be indicative of future events, trends or performance. This article is based on certain assumptions and reflects prevailing conditions as at the time of publication, which are subject to change at any time without notice. The author and publisher of this article as well as any other parties associated with this article make no representation or warranty of any kind, whether express, implied or statutory, in respect of this article and accept no liability or responsibility for the completeness or accuracy of this article or any error, inaccuracy or omission relating to this article and/or any consequence, injury, loss or damage howsoever suffered by any person relating to this article, in particular, arising from any reliance by any person on this article. Publishers or platforms may be compensated for access to third party websites.Contact Information:Name: Sonakshi MurzeEmail: Sonakshi.murze@iquanti.comJob Title: ManagerSOURCE: iQuanti Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

ACN Newswire

受邀参加中关村论坛！百望股份以Tax Swift打造全球贸易的”合规路由器”

27 3 月, 2026

近日，2026中关村论坛年会在北京隆重举行。作为国家级科技创新交流合作平台的重要参与者，百望股份受邀出席本次国家级科技创新交流盛会，并在"东盟创新合作发展论坛"中发表了重磅主题演讲。论坛上，百望股份聚焦跨境贸易合规痛点，推介全球智能税务合规平台Tax Swift。它内置百望自研的AI税务引擎、百望指数与国家适配器，依托覆盖全球的税务规则知识库，动态监控、AI分析、自动更新，打造起全球贸易的"合规路由器"，为国际经贸合作注入合规新动能。论坛聚焦科技创新，跨境合规成全球贸易核心命题2026年中关村论坛年会，是经国务院批准、以"科技创新与产业创新深度融合"为年度主题，由科技部、国家发展改革委、工业和信息化部、国家国资委、中国科学院、中国工程院、中国科协和北京市政府共同主办。大会汇聚了100多个国家和地区的全球顶尖科学家、企业家及国际组织代表，上千名嘉宾共同搭建起中国与世界科技创新交流的桥梁。作为本次中关村论坛的重要平行论坛，东盟创新合作发展论坛聚焦中国与东盟科技创新协同、产业融合发展、跨境贸易便利化等核心议题，汇聚东盟各国政、产、学、研各界代表，交流研判破解区域经贸合作中的共性难题。在主题演讲环节，百望股份围绕着"AI赋能中企出海：构建全球化合规新底座"展开了深度分享。当前，全球贸易一体化进程不断加快，跨国经营的业务蓬勃发展，但税务合规难题始终是制约全球贸易高效推进的关键瓶颈。尤其是东盟这样的活力经济体，区域内各国经贸往来频繁，跨境交易规模持续攀升，市场主体对于交易效率、交易合规有着更高的需求和更迫切的期待，而区域内各国税务政策、技术标准的差异，却成为了制约中国-东盟跨境贸易提质增效的重要因素。从实践来看，国际贸易税务合规难题呈现多元化、复杂化态势：- 语言与格式壁垒凸显，不同标准、规范让企业票据解读成本高、理解易出偏差；- 各国财税政策碎片化严重，差异性的税种、税率、申报流程，让企业难以精准掌握；- 技术标准不统一，系统接口、数据传输缺乏规范，各类操作繁琐且效率低下；- 跨境交易链条长、涉及主体多，企业难以实现全流程风险检测；这些难题不仅增加了企业跨境经营的成本，更成为制约企业融入全球产业链、拓展国际市场的关键瓶颈。百望股份的Tax Swift平台，正是破解合规困境、保驾跨境贸易的全新技术创新，尤其为中国-东盟跨境贸易合规发展提供了高效可行的思路。Tax Swift重磅亮相，全链路一站式赋能国际贸易合规作为百望股份的深耕全球税务合规领域、布局国际化市场的核心成果，Tax Swift一次适配，就可帮助企业构建起覆盖"票据处理-纳税申报-风险管控"的全链路跨境税务合规服务体系：一是全球AI全链路票据处理能力，可打破语言与格式壁垒。国际化引擎、发票引擎、税务引擎与国家适配器，四重引擎自动协同运转，完成智能算税、智能识别等，一套架构适配全球业务场景。企业无需手动干预任何细节，即可完成多语言、多币种、多时区的票据管理工作，完美适配东盟各国票据规范与业务场景。二是全球AI一键申报，打通跨境税务申报便捷通道。Tax Swift现已与20多国国税局直连，全球税务规则知识库动态更新、AI分析引擎自动扫描规则变化，联动发票识别引擎与全球交易计税规则引擎实时响应，将全球申报工作压缩成一个动作：一键登录，自动填饱，实时同步状态，可大幅提升东盟跨境贸易税务申报效率。三是全球AI税务顾问，提供全周期政策支撑。平台内置超3万条国际财税规则，覆盖200+国家税种与费金，通过实时联动发票引擎与税务引擎，实现AI自动解读、自动更新，及时识别和处置异常变化，帮助企业精准把握区域政策动态、规避合规风险，尤其针对东盟各国税务政策的更新与调整实现实时响应。三大AI能力模块的协同运作，为企业建立起全球合规洞察的能力，构筑起清晰可控的合规管理边界。当前，全球贸易格局深度调整，合规已成为企业跨境经营的核心竞争力，百望股份"贸易无国界、纳税有主权"的理念，精准契合了出海企业的合规需求。依托全球化战略布局，百望股份持续推进TaxSwift产品迭代落地，自2025年8月启动以来，产品已完成1.0版本全球电子发票布局，并在2026年加速海外数据中心与算力中心部署，加速东南亚、欧盟、中东等区域市场的拓展，向着建设覆盖80+CTC国家的全球AI票税合规平台快速演进。而东盟作为百望股份全球化出海的先锋阵地，凭借区域内旺盛的跨境贸易合规需求，成为 Tax Swift 落地应用的核心市场，已有众多企业与百望股份达成深度合作，其中越南、新加坡、印度尼西亚等东盟国家的企业、高校更是与百望携手，共同探索跨境税务合规的数智化解决方案，让 Tax Swift的技术能力与服务体系更好地适配东盟市场需求。依托中关村论坛及东盟创新合作发展论坛的开放平台，更多国际嘉宾尤其是东盟各国代表，对百望股份的数智解决方案有了进一步了解。深耕财税数智领域十余年，百望股份已经累计处理发票数量逾260亿张，对应交易总额高达1188.0万亿元，服务的纳税人识别号数量更是突破了9640万家，这些丰富的实践经验与数据智能领域的深厚沉淀，赢得了与会嘉宾产生了高度关注与广泛认可。未来，百望股份将持续深化Tax Swift平台的迭代升级，重点打磨适配东盟市场的产品能力与服务体系，打造一流的全球税务合规智能体平台，进一步拓展全球服务范围，帮助更多跨境经营的国际企业开拓发展、赢得未来！ Copyright 2026 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

ACN Newswire

Hua Medicine Announces 2025 Annual Results

27 3 月, 2026

- Annual sales of HuaTangNing exceeded 4 million packs, a year-on-year increase of 91%, with revenues reaching RMB 492.9 million, a year-on-year increase of 93%, marking outstanding results from the Company’s fully independent commercialization operation.- Delivered record financial performance, with profit before tax reaching RMB 1,106.4 million; maintained a robust bank balance and cash position of RMB 1,092.3 million at year-end, laying a solid foundation for sustainable operations and growth.- Gross margins rose to 56.9%, and selling expenses as a percentage of revenue were optimized to 33.6% from 59.9%, significantly enhancing profitability.- HuaTangNing  renewed its listing in the new National Reimbursement Drug List (NRDL) at the same price in 2025 for the calendar years 2026 and 2027, reaffirming its clinical and innovative value.- With the approval of PTE, market exclusivity in China granted another 5 years to April 2034, further strengthening commercial certainty.- Dorzagliatin was approved for commercialization in Hong Kong as HYHOMSIS®, accelerating its global expansion toward South-East Asia.- Multiple real-world evidence published to demonstrate therapeutic advantage of dorzagliatin.- Continuous expansion of therapeutic potential of glucose homeostasis and initiation of new first-in-disease indications study covering diabetes prevention, rare diseases, mild cognition impairment and frailty.SHANGHAI, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) – Hua Medicine ("the Company", Hong Kong Stock Exchange Stock Code: 2552) announces the audited consolidated results of the Company and its subsidiaries for the year ended December 31, 2025 (the “Reporting Period”). During the Reporting Period, the commercialization of HuaTangNing (dorzagliatin tablets), the Company’s core product – the global first-in-class innovative anti-diabetes medicine, glucokinase activator (GKA) – advanced comprehensively across all fronts, the Company’s independent commercialization team was efficiently and seamlessly established in its first year of operations, the Company’s R&D pipeline continued to be enriched, and the Company’s financial performance achieved a historic breakthrough, successfully entering a new stage of profitability, injecting strong momentum into the innovative development of the global diabetes treatment field.Dr. Li CHEN, Founder and CEO of Hua Medicine, stated: “2025 is a remarkable year in the commercialization operation of Hua Medicine. The Company has successfully advanced from R&D to commercialization driven organization and achieved the fully independent capacity in commercialization of global first in class novel glucose homeostasis regulator HuaTangNing. With strong market execution and product competitiveness, we have achieved nearly triple-digit growth in sales volume and revenue over 2024 when the commercialization was farmed out to sales and marketing partners. At the same time, the Company has made key progress in global market expansion through registration of drozagliatin in Hong Kong and position it toward 700 M population in south-east Asia. We continue to expand the clinical application of glucose homeostasis regulation technology and engage in new indications such as early-stage Alzheimer’s disease and Frailty. The first-in-disease efforts in GCK-MODY and Frailty set the new innovation course of Hua Medicine in the next 5 years.” Business Highlights and Operational Progress- Fully Powered Commercialization, Historic Breakthrough in ProfitabilityOn January 1, 2025, the Company assumed full responsibility for the commercialization of HuaTangNing, allowing the company to consolidate both operational and strategic control over market execution in China. The Company successfully built a professional sales team covering 10 sales regions around the country, focusing on marketing, medical affairs and commercial operation. Through an AI-empowered digital commercialization platform, operational efficiency and sales productivity were greatly enhanced, injecting new vitality into the Company’s commercial development.Reimbursement coverage under the NRDL has significantly increased accessibility, especially in Tier 2 and Tier 3 hospitals, and played a critical role in accelerating patient adoption. Since its launch in October 2022, HuaTangNing has been prescribed to over 500,000 patients through 3,000+ hospitals, community centers, pharmacies and online channels.Sales performance exceeded expectations, with 4.011 million packs of HuaTangNing sold during the reporting period, representing a 91% increase over the fiscal year 2024. This growth was achieved at the same price for both periods, underscoring strong demand and successful execution of Hua’s commercial strategy.In terms of profitability, the Company’s gross profit reached approximately RMB280.4 million, a year-on-year increase of 125%. Thanks to expanded production scale and optimized manufacturing processes, the Company’s gross margin improved to 56.9%,  increasing by 8.2 percentage points as compared to 48.7% for the year of 2024. Selling expenses increased only by RMB12.3 million to RMB165.5 million, reflecting a significant positive trend towards profitability when our selling expenses in the 2025 fiscal year represents only 33.6% of revenue, whereas in the 2024 fiscal year, our selling expenses represented approximately 59.9% of revenue. In fiscal year 2025, our commercialization efforts achieved profits of approximately RMB114.9 million (as defined by gross profits less selling expenses). Although we expect to continue to increase personnel to our commercialization team, we expect this profitability trend in our commercial operations in mainland China to continue.Following the termination of the collaboration with Bayer at the end of 2024, dorzagliatin achieved a record-high sales volume. Profit before tax increased to RMB1,106.4 million for the fiscal year 2025. We ended fiscal year 2025 with a cash position of approximately RMB1,092.3 million.- Accelerated Global Layout, Strengthened Core Rights and InterestsThe Company took a key step in global expansion. On February 27, 2026, dorzagliatin (trade name: MYHOMSIS®, was successfully approved for marketing by the Hong Kong regulatory authority. The Company plans to officially launch the product in the Hong Kong market by the middle of 2026 and further expand to Asian regions. In addition, the Company submitted a new drug registration application in Macau in 2025.The Company also made new progress in intellectual property protection. In February 2026, the patent term extension (PTE) application for dorzagliatin was formally approved by the China National Intellectual Property Administration, thereby the core patent protection period of dorzagliatin extended to April 2034 and an additional 5-year market exclusivity obtained, which provides a strong guarantee for the product’s long-term market competition.In 2025, dorzagliatin was recognized as national innovation and an effective therapy for chronic diseases by the regulatory authorities in China. Accordingly, the same NRDL price was offered for the calendar years 2026 and 2027. Reimbursement coverage under the NRDL has significantly increased accessibility, especially in Tier 2 and Tier 3 hospitals, and played a critical role in accelerating patient adoption. The Company will continue to safeguard the product’s market competitiveness and patient accessibility and accelerate the popularization of the drug among patients.- Advancement of Real-World Studies, Continuous Validation of Clinical ValueReal-world evidence (RWE) studies continue to corroborate the key role of dorzagliatin in improving glucose-dependent pancreatic islet secretion function, and demonstrate its efficacy in diabetes prevention, remission, and delaying or preventing diabetes complications.The RWE study sponsored by Hua Medicine HMM0701 with 380 T2D patients was fully enrolled in 2025. The interim analysis, as reported at the 2025 American Diabetes Association (ADA), showed that 86% of such patients were taking two or more antidiabetic drugs and 41% of such patients were using insulin. After a 6-month treatment, a significant improvement of glycemic control was observed with HbA1c reduction from 8.1% to 7.3% with the mean time-in-range (TIR) levels increasing to over 70%. Thus far, the studies have demonstrated that when dorzagliatin is administered in combination with other antidiabetic drugs, such patients have experienced significantly improved post-meal glucose levels and improved β-cell function.Separately, a mechanistic study with dorzagliatin (employing double-tracer measurement) was conducted in the United States to provide scientific evidence of hepatic glycogen formation in T2D patients with an average of 17 years of diagnosed diabetes. In this study, patients were treated with dorzagliatin twice daily for 6 weeks. The results showed that dorzagliatin increased direct glucose flux to hepatic glycogen implying the improvement of restoration of hepatic Glucokinase (GK) function. Together with the clinical research data that dorzagliatin improves early phase insulin release and GLP-1 secretion, recovery of hepatic glycogen synthesis in T2D patients offers an important path in controlling post-meal glucose excursion and provides a unique opportunity in controlling diabetes complications, such as diabetes kidney diseases and mild cognition impairment.The RWE sponsored by Hua Medicine (HMM0601) has completed clinical trials with over 2,000 subjects, with average diabetes duration of 7.9 years and above 30% having disease duration more than 10 years. The initial results suggest that dorzagliatin is safe and well tolerated in Chinese T2DM patients. There were no new adverse effects observed in the study and the incident rate remains as low as what was observed in Phase III clinical trials. Patient adherence was generally high, with a mean adherence rate of approximately 95%. In this study, 80% of the participants have used one or more oral anti-diabetes medicine, and 20% used insulin. Dorzagliatin demonstrated good efficacy and safety not only in the overall population but also in elderly, obese, and hyperglycemic patient populations, whether used as monotherapy or in combination with metformin, SGLT2 inhibitors, insulin, and other medications. The topline results will be reported at the 2026 American Diabetes Association.- Deepened Clinical R&D, Continuous Expansion of New IndicationsNew Indication for Dorzagliatin – MODY-2 Patients.Medical experts in mainland China and Hong Kong have conducted independent clinical and preclinical studies of dorzagliatin for MODY-2 treatment. MODY-2, also called GCK-MODY, is a monogenic disease in which patients have a genetic defect of glucokinase gene (GCK) which results in elevated blood glucose and significant reduction of the second phase insulin secretion. The population of GCK-MODY patients is approximately 1.7 million in China. These patients are diagnosed with diabetes at a young age and represent an unmet medical need given that currently available medications are not effective. In clinical studies with MODY-2 patients, China investigators have reported that dorzagliatin is effective in reducing blood glucose levels to normal levels in MODY-2 patients who previously failed to manage their elevated blood glucose levels when treated with metformin, TZD, DPP-IV inhibitors, and SGLT-2 inhibitors. Additional results demonstrated that a single dose of dorzagliatin improved overall glucose sensitivity and second phase insulin secretion significantly in GCK-MODY patients, suggesting a unique mechanism of action of dorzagliatin to regulate GLP-1 secretion. Based on such results, Hua Medicine has communicated and reached a consensus with the CDE at NMPA to file the IND submission of dorzagliatin for MODY-2 patients in 2026.Dorzagliatin for Diabetes Prevention.Prevention of diabetes is an important focus at Hua Medicine. There are approximately 1.12 billion people living with prediabetes worldwide. We have initiated SENSITIZE 3 clinical study in Hong Kong in pre-diabetic (IGT) subjects and in early diabetes patients. These studies represent first-in-disease studies. In this double-blinded placebo-controlled study, we will evaluate the blood glucose management and pancreatic function under IVGTT and OGTT conditions to better define the clinical treatment baseline and endpoints. We expect to complete this study in 2026 and explore the opportunity to file IND applications of dorzagliatin for diabetes prevention in China and Asian Pacific regions thereafter. Dorzagliatin for Neurodegenerative Diseases.MCI shows approximately 15.5% prevalence among elderly people in China and approximately 22% in the US, and is common in T2D patients with a 45% incidence rate. The development of dorzagliatin for neurodegenerative disease is a new focus in our drug discovery efforts. Through the Genome-Wide Association Study (GWAS) and Mendelian Randomization (MR) study, we have realized the important role of GCK gene activation in the prevention of memory loss and cognitive impairment in humans. It has also come to our attention that post-meal glucose excursion is closely related to Alzheimer disease and dementia. The bio-energy balance in the brain is largely dependent on the glucose homeostasis control in the peripheral organ and the neural network communication in the central and peripheral system via spatial temporal management. Impaired glucose homeostasis and diabetes conditions result in a reduction of glucose transporter expression and insulin receptor expression in the brain, which can be prevented by low dose dorzagliatin. We have realized the potential of dorzagliatin in the treatment of mild cognitive impairment (MCI) and will initiate these first-in-disease clinical studies in the future.Dorzagliatin for Frailty.Frailty is an age-related geriatric syndrome characterized by reduced tolerance to internal and external stressors. Approximately 17% of Americans and 11% of Asians over the age of 50 suffer from frailty, while pre-frailty affects roughly 50% and 47% of these populations, respectively. It is not a single-organ disease, but the consequence of dysregulated multisystem homeostasis. Genetic evidence supports the causal effects of glucokinase (GK) activation on lowering frailty risk. We plan to initiate clinical studies in the future to advance dorzagliatin’s application in frailty.Development of combination therapy for diabetes and complications.Dorzagliatin rescues pancreatic function in glucose insulin secretion and GLP-1 secretion, as evidenced by clinical and basic research results. It also improves hepatic insulin sensitivity and reduces hepatic insulin resistance through recovery of hepatic glycogen synthesis in T2D patients. The combination of dorzagliatin with DPP-IV inhibitors, SGLT-2 inhibitors, and GLP-1 agonists have demonstrated effective regulation of lipid metabolism. Studies in combination with anticancer PI3K inhibitors have also offered unique benefits for glucose homeostasis management.- Diversified Product Pipeline, Innovative Layout for Future GrowthHua Medicine continues to enrich its pipeline layout based on core products. The Company has accelerated the R&D of a fixed-dose combination (FDC) of dorzagliatin and metformin as a twice-daily therapy for Type 2 diabetes patients with inadequate glycemic control on metformin alone, to further improve patient medication compliance. The product is supported by the strong results of the loose-dose combination in both Phase III clinical trials and real-world use. The Company has submitted an IND application to NMPA, and the GMP commercial manufacturing process has been successfully carried out, preparing for the pivotal bioequivalence study for NDA filing in 2027. Clinical studies have shown that the combination of dorzagliatin and metformin can better control blood glucose, reduce postprandial blood glucose and improve fasting blood glucose, providing new clinical value for optimizing blood glucose homeostasis endpoints.We have advanced our 2nd generation GKA as a once daily therapy for patients with obesity, leveraging dorzagliatin effects in improved glucose-stimulated GLP-1 secretion in the pancreas and in the intestine. The MAD study of the 2nd generation GKA was initiated in the United States with first-patient-in in December 2025, and we expect to report topline data by the middle of 2026.Meanwhile, the Company is also exploring combination therapy regimens of dorzagliatin with GLP-1 receptor agonists, SGLT-2 inhibitors and other drugs. In a recently published clinical trial in China, researchers reported the superior benefits of our dorzagliatin in combination with semaglutide as compared to semaglutide alone in a 12-week study. The combination group showed superior results across several key measures, including glycemic control, bodyweight related indicators and β-cell function.Financial Summary- Revenue generated by the Company was approximately RMB 492.9 million from the sale of approximately 4.011 million packs of HuaTangNing, increases of approximately 93% and 91% respectively, as compared with the year ended December 31, 2024.- Gross profit generated by the Company for the year ended December 31, 2025, was approximately RMB280.4 million, representing an increase of approximately 125%, as compared with the year ended December 31, 2024, and gross margins rose to 56.9%.- Profit before tax increased by approximately 542% to approximately RMB1,106.4 million for the year ended December 31, 2025, as compared with the year ended December 31, 2024.- Bank balances and cash position was approximately RMB1,092.3 million as of December 31, 2025.- Expenditures incurred by the Company for the year ended December 31, 2025, were approximately RMB433.4 million.Forward-Looking StatementsThis document contains statements regarding Hua Medicine's and its products' future expectations, plans and prospects. Such forward-looking statements relate only to events or information as of the date on which the statements are made in this document and are subject to change in light of future developments. Except as required by law, the Company shall not be obligated to update or publicly revise any forward-looking statements or unforeseen events after the date of such statements, whether as a result of new information, future events or other circumstances. Please read this document carefully and understand that actual future performance or results of the Company may differ materially from expectations due to various risks, uncertainties or other statutory requirements.About Hua MedicineHua Medicine (The “Company”) is an innovative drug development and commercialization company based in Shanghai, China, with companies in the United States and Hong Kong. Hua Medicine focuses on developing novel therapies for patients with unmet medical needs worldwide. Based on global resources, Hua Medicine teams up with global high-calibre people to develop breakthrough technologies and products, which contribute to innovation in diabetes care. Hua Medicine's cornerstone product HuaTangNing (dorzagliatin tablets), targets the glucose sensor glucokinase, restores glucose sensitivity in T2D patients, and stabilizes imbalances in blood glucose levels in patients. HuaTangNing was approved by the National Medical Products Administration (NMPA) of China on September 30th, 2022. It can be used alone or in combination with metformin for adult T2D patients. For patients with chronic kidney disease (CKD), no dose adjustment is required. It is an oral hypoglycemic drug that can be used for patients with Type 2 diabetes with renal function impairment. In February 2026, dorzagliatin (Trade name: MYHOMSIS®,) was approved for marketing by the Pharmaceutical Services of the Department of Health of the Government of the Hong Kong Special Administrative Region of China.For more informationHua MedicineWebsite: www.huamedicine.comInvestorsEmail: ir@huamedicine.comMediaEmail: pr@huamedicine.com Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

ACN Newswire

华领医药公布2025年全年业绩

27 3 月, 2026

- 华堂宁(R)全年销量超400万盒，同比增长91%，销售额达4.929亿元，同比增长93%，公司全面自主商业化运营成效卓著。- 实现创纪录盈利，税前盈利达11.064亿元；现金余额稳健，截至年末达 10.923亿元，为持续运营发展奠定坚实基础。- 毛利率提升至56.9%，销售开支占比从59.9%优化至33.6%，盈利能力显著增强。- 华堂宁(R)原价续约新版医保目录，2026-2027年维持2025年的价格不变，临床价值和创新价值再获认可。- 随着PTE获批，中国市场独占权获5年延期至2034年4月，商业确定性进一步提升。- 多格列艾汀（HYHOMSIS(R) ，華領片(R)）获得香港地区上市批准，加速其面向东南亚的全球扩张进程。- 发布多项真实世界证据，证实多格列艾汀治疗优势。- 持续拓展血糖稳态治疗潜力，启动多项全新的疾病首创新适应症研究，研究范围涵盖糖尿病预防、罕见病、轻度认知障碍及衰弱症领域。上海, 2026年3月27日 - (亚太商讯 via SeaPRwire.com) - 华领医药（"公司"，香港联交所股份代号：2552）宣布公司及其附属公司截至2025年12月31日止年度（"报告期"）经审核的综合业绩。报告期内，公司核心产品、全球首创抗糖尿病新药、葡萄糖激酶激活剂（GKA）华堂宁(R)（多格列艾汀片）实现全方位推进，公司自主商业化团队于运营首年即实现高效组建和运转，研发管线持续丰富，财务表现实现历史性突破，成功迈入盈利新阶段，为全球糖尿病治疗领域的创新发展注入强劲动力。华领医药创始人、CEO陈力博士表示："2025年是华领医药商业化运营中的意义非凡的一年。公司成功完成从研发驱动型组织向商业化驱动型组织的转型，具备了全球首创新药、血糖稳态调节剂华堂宁(R)的完全自主商业化运营能力。凭借强劲的市场执行力与产品竞争力，相较于2024年将商业化业务委托给营销合作伙伴的阶段，公司的销量与营收实现了近三位数的增长。与此同时，通过推动多格列艾汀在香港的注册工作，公司在全球市场拓展方面取得了关键性进展，我们将向覆盖7亿人口的东南亚地区进行市场布局。我们持续拓展血糖稳态调控技术的临床应用场景，积极布局早期阿尔茨海默病、衰弱症等新适应症领域。针对GCK-MODY及衰弱症开展的疾病首创新药研发工作，将为华领医药未来五年的创新发展划定全新方向。"业务亮点与运营进展- 商业化全面发力，盈利实现历史性突破2025年1月1日起，公司正式全面接管华堂宁(R)在中国的商业化工作，获得全部运营与战略主导权，公司成功搭建了专业的销售团队，覆盖全国10个销售区域，专注于产品营销、医学事务及商业运营。通过人工智能赋能的数字商业化平台，运营效率与销售生产力大幅提升，为公司商业化发展注入新活力。受益于国家医保药品目录的持续广泛覆盖，华堂宁(R)在二级和三级医院的处方量显著增长，患者可及性不断提高，通过3000多家医院、社区卫生中心、药房和线上渠道，惠及超过50万名患者。报告期内，产品销量达401.1万盒，同比增长91%；销售额达4.929 亿元，同比增长93%，在单价保持稳定的情况下，充分印证了市场需求的强劲增长和自主商业化团队的高效执行能力。盈利能力方面，2025年，公司毛利达到2.804亿元，同比增长125%，得益于生产规模扩大及制造工艺优化，公司毛利率从2024年的48.7% 提升至56.9%，增加8.2个百分点；销售开支仅增长1230万元至1.655亿元，占收入比例优化至33.6%，较2024年的59.9%大幅下降；商业化业务实现约1.149亿元盈利（按毛利扣除销售开支计算）。公司预期仍将持续扩充商业化团队规模，但商业化运营的盈利趋势也将持续增长。在2024年底终止与拜耳合作后，多格列艾汀销售额创历史新高，报告期内，公司税前盈利增加至人民币11.064亿。截至2025年末，现金结余约为人民币10.923亿元，稳健的现金情况为公司持续发展奠定了坚实基础。- 全球布局加速推进，核心权益得到强化公司全球化布局迈出关键步伐。2026年2月27日，多格列艾汀（香港地区商品名：MYHOMSIS(R)，華領片(R)）成功获得香港监管机构的上市批准，公司计划2026年中正式在香港市场推出该产品，并将进一步向亚洲地区拓展。此外，公司已于2025年向澳门药监局递交華領片(R)（MYHOMSIS(R)）的新药上市申请。公司在知识产权保护方面也再获进展。2026年2月，中国国家知识产权局批准多格列艾汀专利期限补偿（PTE）申请，核心专利保护期延长至2034年4月，新增5年市场独占权，为产品长期市场竞争提供有力保障。2025年，多格列艾汀获中国监管机构认定为国家级创新药及慢病有效治疗药物，国家医保局已确认，2026-2027年，华堂宁(R)的国家医保目录价格维持不变，公司将持续保障产品的市场竞争力和患者可及性，尤其在二级和三级医院，加速患者的用药普及。- 真实世界研究推进，临床价值获持续验证真实世界证据（RWE）研究持续佐证多格列艾汀在葡萄糖依赖性胰岛分泌功能改善中的关键作用，并显示其在糖尿病预防、缓解及延缓或预防糖尿病并发症方面的功效。HMM0701已完成入组，共招募380名2型糖尿病患者。2025年6月，在美国ADA年会上发表的中期分析结果显示，86%的患者同时服用两种或以上降血糖药物，41%的患者使用胰岛素。经6个月治疗后，血糖控制明显改善，糖化血红蛋白由8.1%降至7.3%，平均TIR（目标范围内时间）提升至70%以上。迄今为止的研究显示，多格列艾汀与其他降糖药物联合使用时，患者的餐后血糖水平和β细胞功能均显著改善。另外，在美国进行的多格列艾汀机制研究（采用双示踪剂测量法），为平均确诊糖尿病17年的2型糖尿病患者的肝糖原生成提供了科学证据。在该研究中，患者每日服用两次多格列艾汀，持续6周。结果显示，多格列艾汀能增加葡萄糖直接流入肝糖原的通量，意味着其有助于恢复肝脏GK功能。结合临床研究数据显示，多格列艾汀可改善早期胰岛素释放和GLP-1分泌，恢复2型糖尿病患者的肝脏GK功能，不仅为控制餐后血糖波动提供重要途径，并在控制糖尿病并发症（如糖尿病肾病变及轻度认知障碍）方面提供独特契机。HMM0601研究已经完成临床试验，共纳入2000名受试者，平均患病时间为7.9年，其中超过30%患病时间超过10年。初步结果显示，多格列艾汀在中国2型糖尿病患者中安全性、耐受性良好。研究中未观察到新的不良反应，不良反应发生率维持在III期临床试验中观察到的低水平，患者的用药依从性普遍较高，平均依从率约为95%。在本研究中，80%的受试者已使用一种或多种口服降血糖药，20%的受试者使用胰岛素。多格列艾汀不仅在整体患者群体中展现出良好的疗效及安全性，在老年、肥胖及高血糖患者群体中同样有效，无论作为单药治疗或与二甲双胍、SGLT-2抑制剂、胰岛素及其他药物联合使用。顶线结果将于2026年ADA年会上发表。- 临床研发持续深化，新适应症不断拓展多格列艾汀用于治疗MODY-2患者。中国内地及香港地区医学专家已独立开展多格列艾汀用于MODY-2治疗的临床研究及临床前研究。MODY-2（又称GCK-MODY）是一种单基因疾病，患者因葡萄糖激酶基因(GCK)存在遗传缺陷，导致血糖升高及第二时相胰岛素释放显著减少。在中国，MODY-2患者群体规模约为170万人。此类患者确诊糖尿病时年龄偏小，且由于现有治疗药物疗效不佳，这一患者群体存在未被满足的医疗需求。中国研究人员在针对MODY-2患者的临床研究中报告指出，对于先前使用二甲双胍、TZD、DPP-4抑制剂及SGLT-2抑制剂仍无法控制高血糖的MODY-2患者，多格列艾汀能有效将血糖降至正常水平。其他结果显示，单剂量多格列艾汀可显著改善这类患者的整体葡萄糖敏感性及第二时相胰岛素分泌，表明多格列艾汀具有调节GLP-1分泌的独特作用机制。基于以上结果，华领医药已与国家药品监督管理局（NMPA）药品审评中心沟通，将于2026年提交多格列艾汀用于MODY-2患者的IND申请。多格列艾汀用于糖尿病预防。糖尿病预防是华领医药的重要研发重点。公司已于香港启动针对糖尿病前期糖耐量异常（IGT）受试者及早期糖尿病患者的SENSITIZE 3临床研究。这项双盲安慰剂对照研究将评估受试者在静脉葡萄糖耐量试验及口服葡萄糖耐量试验下的血糖控制及胰岛功能，以更明确界定临床治疗基线及终点指标。我们预计于2026年完成研究后，将在中国及亚太地区探索提交多格列艾汀用于糖尿病预防的IND申请的新机遇。多格列艾汀用于神经退行性疾病。研究显示，中国老年人的轻度认知障碍患病率约为15.5%，美国则约为22%；该症状在2型糖尿病患者中也相当常见，发病率达45%。多格列艾汀用于神经退行性疾病的研究已成为公司药物研发工作的新焦点。通过全基因组关联分析(GWAS)及孟德尔随机化（MR）研究，我们发现GK基因激活在预防人类记忆力衰退及认知障碍方面具有重要作用。同时我们也发现，餐后血糖波动与阿兹海默症及失智症密切相关。血糖稳态异常及糖尿病状况会导致大脑葡萄糖转运蛋白及胰岛素受体表达减少，而低剂量多格列艾汀可预防该功能损伤。我们已确认多格列艾汀在治疗轻度认知障碍方面的潜在价值，并将于未来启动针对该疾病领域的首创疗法的相关临床研究。多格列艾汀用于治疗衰弱症。衰弱症是一种与年龄相关的老年综合症，其特征为对内外应激因子的耐受性降低。约17%的美国人及11%的亚洲人（50岁以上）患有衰弱症，而处于衰弱症前期者则分别约占此两个群组的50%及47%。衰弱症并非单一器官疾病，而是多系统内稳态失调所导致的后果。遗传学证据支持GK激活对降低衰弱症风险具有因果作用。我们计划于未来启动临床研究，以推进多格列艾汀在衰弱症治疗领域的应用。联合用药用于糖尿病及并发症的治疗。临床与基础研究结果显示，多格列艾汀能恢复胰腺在葡萄糖刺激下的胰岛素及GLP-1分泌，也可以通过恢复2型糖尿病患者肝脏葡萄糖激酶功能，改善肝脏胰岛素敏感性并降低肝脏胰岛素抵抗。多格列艾汀与DPP-4抑制剂、SGLT-2抑制剂及GLP-1受体激动剂的联合使用已证明可有效调节脂质代谢，与抗癌PI3K抑制剂联合使用的研究也为血糖稳态管理带来独特优势。- 产品管线丰富多元，创新布局未来增长华领医药在核心产品基础上持续丰富管线布局。依托多格列艾汀与二甲双胍联合用药在III期临床试验和真实世界应用中取得的优异数据，公司加速推进多格列艾汀与二甲双胍固定复方制剂（FDC）的研发。该制剂为每日两次给药方案，适用于单用二甲双胍血糖控制不佳的2型糖尿病患者，旨在以进一步提升患者的用药依从性。公司已向NMPA提交IND申请文件。此外，GMP商业化生产工艺也已成功开展，为2027年新药上市申请的关键生物等效性研究做好准备。临床研究显示，多格列艾汀与二甲双胍联用能够更好地控制血糖，降低餐后血糖，改善空腹血糖，为优化血糖稳态终点提供了新的临床价值。第二代GKA的研发取得重要突破。作为肥胖2型糖尿病患者每日一次治疗的缓释新片剂，公司已在美国启动多格列艾汀多剂量递增（MAD）研究，以探讨第二代GKA在血糖稳态控制方面的疗效及新药的作用机制，首例患者已于2025年12月入组，预计2026年中公布顶线数据。同时，公司还在探索多格列艾汀与GLP-1受体激动剂、SGLT-2抑制剂等药物的联合治疗方案。近期，在一项中国的临床试验中，研究者报告：多格列艾汀联合司美格鲁肽治疗12周，疗效显著优于司美格鲁肽单药治疗。联合治疗组在血糖控制、体重相关指标及β细胞功能等多项关键指标上均表现更优。财务摘要截至2025年12月31日，- 华堂宁(R)全年销量约401.1万盒，相较2024年全年，同比增长91%，实现营收约4.929亿元，同比增长93%。- 毛利约人民币2.804亿元，同比增长125%，毛利率提升至56.9%；- 税前盈利约人民币11.064亿元，较2024年增长542%；- 银行结余及现金约人民币10.923亿元，资金状况稳健；- 总开支约人民币4.334亿。前瞻性声明本文包含有关华领医药以及产品未来预期、计划和前景的陈述。该等前瞻性陈述仅与本文作出该陈述当日的事件或资料有关，可能因未来发展而出现变动。除法律规定外，于作出前瞻性陈述当日之后，无论是否出现新资料、未来事件或其他情况，我们并无责任更新或公开修改任何前瞻性陈述及预料之外的事件。请仔细阅读本文并理解，由于各种风险、不确定性或其他法定要求我们的实际未来业绩或表现可能与预期有重大差异。关于华领华领医药（"本公司"）是一家总部位于中国上海的创新药物研发和商业化公司，在美国、中国香港设立了公司。华领医药专注于未被满足的医疗需求，为全球患者开发全新疗法。华领医药汇聚全球医药行业高素质人才，融合全球创新技术，依托全球优势资源，研究开发突破性的技术和产品，引领全球糖尿病医疗创新。公司核心产品华堂宁(R)（多格列艾汀片）以葡萄糖传感器葡萄糖激酶为靶点，提升2型糖尿病患者的葡萄糖敏感性，改善患者血糖稳态失调。2022年9月30日，华堂宁(R)已获得中国国家药品监督管理局（NMPA）的上市批准，用于单独用药或者与二甲双胍联合用药，治疗成人2型糖尿病。对于肾功能不全患者，无需调整剂量，是一款可用于肾功能损伤的2型糖尿病患者的口服降糖药物。2026年2月，多格列艾汀（商品名：MYHOMSIS(R)，華領片(R)）获得中国香港特别行政区政府卫生署药物办公室的上市批准。详情垂询华领医药网址：www.huamedicine.com投资者电邮：ir@huamedicine.com媒体电邮：pr@huamedicine.com新闻免责声明本材料，如为上下文论述的准确性和完整性，提及在中国上市的产品相关信息的，特别是标识或要求，应遵循中国监管机构批准的相关文件。另外，相关信息不应被解读为对任何药物或者诊疗方案的推荐或者宣传，亦不应替代任何医疗卫生专业人士的医疗建议，涉及医疗的相关事宜务必咨询医疗卫生专业人士。 Copyright 2026 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

ACN Newswire

Unisound Posts Strong First Annual Results Since Listing: Revenue Surges Nearly 30%, H2 Loss Narrows Significantly by Over 90%, Profitability in Sight, Charting a New Course in Native Agentic AI!

27 3 月, 2026

HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) – 26 March, Unisound (09678.HK) announced its audited annual results for the year ended December 31, 2025. As the Company's first annual results announcement since listing, it underscores strong growth momentum and continued improvement in its financial profile.Revenue Mix Continues to Improve, with Faster Growth in H2For the full year of 2025, Unisound achieved total revenue of $175 million, representing a year-on-year (YoY) increase of 29%. Revenue in the second half of the year increased by 33% YoY to $117 million.It is worth noting that the Company's large language model (LLM) business generated a full-year revenue of $88.43 million, surging by over 10 times YoY. In particular, this business contributed approximately $72.49 million in H2 revenue, five times the level recorded in H1, demonstrating a compelling capacity for large-scale commercial application.Losses Narrowed Significantly, Making the Path to Profitability Increasingly ClearAlongside the rapid revenue growth, the Company's losses improved markedly. In the second half of 2025, the Company's net loss narrowed by 84% YoY, and its adjusted loss narrowed by 92% YoY, approaching break-even. This reflects the Company's ongoing improvements in cost control and operational efficiency.Simultaneously, some of the Company's operating metrics saw marked improvement. The adjusted expense ratio declined significantly by 10 percentage points YoY, while selling expenses decreased rather than increased and accounted for only 5.4%, highlighting a clear improvement in cost-to-efficiency ratio. In 2025, revenue per employee reached $365,300, up 25% YoY from $292,900 in 2024. Employee productivity continued to lead the industry, clearly underscoring the Company's core strengths in technology-driven, lean operations.Dual-Engine Strategy Gains Traction, with AI in Healthcare and AI in Daily Life Advancing in TandemIn 2025, driven by both technological breakthroughs and policy tailwinds, global demand for AI continued to rise. Unisound adhered to its "Strong Foundation Model + Deep Application" strategy, continued to strengthen its multimodal technology foundation, and drove the continuous elevation of the global influence of its proprietary large model matrix in fields such as healthcare, speech, and OCR.On the commercialization front, the Company leveraged its AI-native organization to accelerate business execution, and its dual-engine strategy in AI in Healthcare and AI in Daily Life delivered notable results. During the reporting period:The AI in Daily Life business achieved revenue of $140 million, a YoY increase of 30.8%. Among this, the Transportation segment recorded nearly 40% YoY growth. At present, AI agent applications based on the Shanhai large model have been deployed in more than 10 cities, including Qingdao, Ningbo, Shenzhen and Nanning. In addition, cumulative AI chip shipments exceeded 110 million units, further validating the Company's scale capabilities in endpoint AI products.The AI in Healthcare business achieved revenue of $35.38 million, a YoY increase of 22.3%, with average revenue per customer growing by 53.2% YoY. In 2025, over 70% of the hospitals the Company collaborated with were tertiary hospitals, and more than one-third of customers had maintained continuous cooperation for over three years. The medical-record entry and generation products powered by the medical large model delivered a 10-fold YoY increase in full-annual medical record generation at a single campus of a leading Class III hospital. The commercial insurance AI agent platform recorded a 37-fold YoY increase in case processing volume. In deep cooperation with a leading insurance group, the expense control rate was effectively raised to approximately 20%, delivering more than $145 million in incremental cost management compared with traditional review methods, comprehensively empowering insurance institutions to refine their medical risk management operations.Continued R&D Investment Strengthens the Technology MoatTo consolidate its industry-leading position, the Company continued to invest heavily in R&D in 2025. Full-year R&D expenses exceeded $55.09 million, accounting for 75% of the Company's adjusted operating expenses, while R&D personnel accounted for 69% of the total workforce. This sustained investment drove breakthroughs across multiple technology areas. For example, in the MedBench 4.0 evaluation, the Company ranked first place in three technical paradigms: "Medical AI Agent," "Medical Large Language Model," and "Medical Multimodal Large Model," earning a "Triple Crown."Outlook: Deepening the Technological Foundation and Expanding Application BoundariesLooking ahead, Unisound will continue to deepen its "Strong Foundation Model + Deep Application" strategy. On the technological front, the Company will continue to increase strategic investment in foundational large models and strive to maintain a world-class level. On the application front, it will use the large-scale expansion of MaaS (Model-as-a-Service) and AI agents as its core growth engine, driving exponential growth in its AI in Daily Life and AI in Healthcare businesses. Meanwhile, the Company is actively exploring the establishment of a recurring revenue system through models such as API calls and Token-based billing, and regards opportunities in consumer-facing (C-end) products as a second growth curve to further expand its commercialization boundaries.Between Q2 and Q3 2026, Unisound will launch a native AI agent large model for programming and office applications, which is expected to double both intelligence density and token production efficiency. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

ACN Newswire

云知声首份年报！2025营收大增近三成 下半年亏损大幅收窄超九成 盈利在望 迈向原生智慧体新征程！

27 3 月, 2026

香港, 2026年3月27日 - (亚太商讯 via SeaPRwire.com) - 3月26日，云知声（09678.HK）发布截至2025年12月31日止年度的经审核全年业绩，展现上市后首份成绩单强劲的增长动能与持续优化的财务结构。营收结构持续优化，下半年增长提速2025年全年，云知声实现总营收12.1亿元人民币，同比增长29%。其中，下半年收入同比增长33%，达8.1亿元。值得关注的是，公司大模型业务全年收入6.1亿元，同比增长超10倍。尤其是下半年，该业务贡献收入约5亿元，为上半年规模的5倍，显示出强劲的规模化落地能力。亏损大幅收窄，盈利路径日渐清晰在营收高速增长的同时，公司亏损状况显著改善。2025年下半年，公司净亏损同比收窄84%，经调整后亏损同比收窄92%，接近盈亏平衡点，反映出公司在成本控制与运营效率方面的持续优化。同时，公司的部分经营指标也得到明显改善。经调整营业费用率较去年同比大幅下降10%，销售费用不升反降，占收入比重仅为5.4%，费效比提升明显。从数据端来看，2025年公司人均产值为252万元/人，相较24年的202万元同比增长25%，人均创效能力持续领跑行业，直观彰显了公司技术驱动、精益运营的核心优势。双轮驱动战略落地，智慧医疗与智慧生活齐头并进2025年，在技术突破与政策红利的双重驱动下，全球人工智能市场需求持续升温。云知声坚持「强基模+深应用」战略，持续夯实全模态技术底座，推动自研大模型矩阵在医疗、语音、OCR等领域的全球影响力不断提升。在商业化层面，公司以AI原生组织推动业务落地，智慧医疗与智慧生活双轮驱动战略成效显著。报告期内：智慧生活业务实现收入9.68亿元，同比增长30.8%。其中，智慧交通业务同比增长近40%，目前，已在青岛、宁波、深圳、南宁等10余个城市落地基于山海大模型的智能体应用。此外，AI芯片累计出货量突破1.1亿颗，进一步验证公司在终端AI产品的规模化能力。智慧医疗业务实现收入2.44亿元，同比增长22.3%，客单价同比增长53.2%。2025年，合作的医院中超70%为三级医院，且超过三分之一客户已经连续合作三年以上；而基于医疗大模型的病历录入与生成产品已在某头部三甲医院单院区实现全年病历生成同比增长10倍；商业保险智能体平台案件处理量同比增长37倍；与头部保险集团的深度合作中，控费率水平有效提升至约20%，相较传统审核方式实现超10亿元级别的增量成本管控，全面赋能保险机构在医疗风控领域的精细化运营。持续加码研发，夯实技术护城河为巩固行业领先地位，2025年公司持续在技术端大力投入，全年研发费用超3.8亿元，占经调整三费的75%；研发人员占比达69%。持续的研发投入在多个技术领域取得突破，如在MedBench 4.0评测中，公司一举斩获"医疗智能体""医疗大语言模型""医疗多模态大模型"三项技术范式第一，荣膺"三冠王"。未来展望：深耕技术底座，拓展应用边界展望未来，云知声将继续深化"强基模+深应用"战略。技术层面，公司将持续加大对基座大模型的战略性投入，力争保持全球一流水平；应用层面，将以MaaS（模型即服务）与智能体的规模化拓展为核心增长引擎，推动智慧生活与智慧医疗业务的指数级增长。同时，公司正积极探索以API调用、Token计费等模式构建经常性收入体系，并将C端产品机会作为第二增长曲线，进一步拓展商业化边界。2026年第二季度，云知声将推出面向编程和办公的原生智能体大模型，并预计能实现智能密度和Token生产效率的倍增。 Copyright 2026 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

ACN Newswire

城建设计公布2025年业绩：收入75.27亿元 综合毛利率提升至19.85%

27 3 月, 2026

香港, 2026年3月27日 - (亚太商讯 via SeaPRwire.com) - 2026年3月26日，北京城建设计发展集团股份有限公司（"本公司"或"公司"，简称"城建设计"，股票代码：1599.HK）董事会（"董事会"）欣然公布本公司及其子公司（合称"本集团"）截至2025年12月31日止年度（"2025年度"或"报告期"）的经审计业绩。2025年，公司面对市场持续下行压力，紧紧围绕高质量发展，迎难而上、实干担当，聚焦主责主业，推动全产业链协同发力，阶段性完成了"十四五"规划主要目标任务，为新征程加快发展积蓄了强劲动能。截至2025年12月31日止年度，本集团实现收入为人民币75.27亿元。本集团实现净利润为人民币5.36亿元，同比上涨1.52%。综合毛利率19.85%，同比上涨1.77%。核心主业与新兴领域协同发力，高端咨询品牌效应显现设计、勘察及咨询板块为本集团的传统和主营核心业务，报告期内，本集团轨道交通领域中标成都27号线二期、厦漳泉城际铁路（厦门段）等重点项目；既有线改造市场成效显著，中标北京、南京、哈尔滨、长春、沈阳等一批代表性项目，市场份额保持领先；高端咨询品牌效应持续显现，成功承担了香港铁路标准、北京三期线网技术标准等标杆项目，专业服务能力稳步提升；境外业务扎实推进，在香港、新加坡、安哥拉、哈萨克斯坦、哥伦比亚持续获取订 单，新签合同额突破人民币1亿元；民建、市政设计走特色化发展之路，在居住建筑、大型TOD、校园、道路等传统领域精耕细作，积极向展陈、城市更新、水环境治理领域延伸布局。截至2025年12月31日止年度，本集团设计、勘察及咨询板块业务收入人民币40.89亿元。其中城市轨道交通工程板块收入人民币29.38亿元，工业与民用建筑和市政工程板块收入人民币11.51亿元。本集团工程承包业务板块专注于服务城市轨道交通建设项目和相关基础设施建设项目，2025年，本集团中标北京轨道交通R4线一期北段01标、03标、M101线05标、市郊铁路东北环线03标等项目，进一步巩固了北京核心市场，在手工程承包项目主要集中在北京、广州、重庆、乌鲁木齐及青岛等城市。截至2025年12月31日止年度，本集团工程承包业务板块实现收入人民币34.38亿元。新建项目与存量改造双线发力，中标额突破81亿元，在手订单储备充足2025年，轨道交通行业面临市场持续下行、招标规模显著缩减、行业竞争加剧及宏观经济形势不确定性增强的局面，公司始终全力以赴力争中标轨道交通新建项目，尤其注重稳固北京区域市场份额。在守住基本盘的同时，积极布局既有线改造、城市更新、能源、数字化及智慧等其他高潜力板块，以应对市场变化并提升抗风险能力。截至2025年12月31日，公司中标金额人民币81.71亿元，其中设计、勘察及咨询业务板块中标人民币26.39亿元，工程总承包板块中标人民币55.32亿元。报告期末公司在手合同额为人民币251.43亿元。2026年展望：锚定"十五五"开局，推动高质量发展2026年是"十五五"开局之年，面对深刻变化的市场形势和艰巨繁重的发展任务，我们要积极把握战略机遇，主动适应行业发展新格局，以稳中求进为总基调，以推动高质量发展为主题，以改革创新为根本动力，锚定打造"以设计为引领的城市建设综合服务商"战略目标，确保"十五五"开好局、起好步。有关城建设计北京城建设计发展集团股份有限公司（股份代码：1599.HK）是国内第一家以城市轨道交通设计咨询为引领的H股上市企业。公司前身是北京城建设计研究总院成立于1958年，是为中国首条地铁北京地铁1号线的勘察设计而成立。拥有国内设计勘察行业最高资质—综合甲级资质。作为行业龙头和市场规范的制定者，公司由成立至今仍保持市场占有率第一的位置。基本业务涵盖投融资、勘察设计咨询、工程总承包、科技产业化、运营管理的城市轨道交通全产业链。公司市场覆盖了全国已批复轨道交通建设规划城市的80%，业务拓展到了国内近70个城市，在50多个城市拥有分支机构。新闻垂询：千里国际顾问有限公司fancywang@maxima.hk Copyright 2026 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

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心玮医疗2025年业绩：净利润8334万元 扭亏为盈

27 3 月, 2026

香港, 2026年3月27日 - (亚太商讯 via SeaPRwire.com) - 2026年3月26日，心玮医疗（06609.HK）公布了2025年业绩公告。2025度，公司收入4.08亿元，同比增长46.9%，净利润8334万元，较上年度亏损约1362万元实现重大扭亏为盈。这一转变主要由于公司在缺血性卒中、出血性卒中及介入通路三大业务板块均实现了收入的快速增长，同时公司的经营效率进一步提升。2025年，公司的缺血性卒中业务收入同比增长31.8%，主要由于：(1)公司具有差异化竞争优势的颅内血栓抽吸导管得到临床的广泛认可，大腔抽吸及级联抽吸技术(CATCH)被纳入《急性缺血性卒中血管内治疗技术中国专家共识2025》，产品进入超过450家医院使用，收入规模快速提升；(2)成熟产品在纳入集采后，销量快速增长。在出血性脑卒业务中，公司已构建完整动脉瘤治疗解决方案。公司的颅内支架（获NMPA创新医疗器械认定）在首个商业化年度累计进入约500家医院使用，带动栓塞弹簧圈的市场份额快速提升。同时，公司的血流导向装置于2025年获NMPA批准上市，实现临床推广和应用。基于前述原因，公司的出血性卒中业务收入在2025年同比增长223.2%。在介入通路业务中，公司的明星产品血管封堵器累计进入超过1800家医院使用，年终端医院临床使用量超过20万条，在2025年实现单产品收入过亿。与此同时，公司正推动第二代血管封堵器的开发和商业化，以继续扩大市场份额。公司的毛利率从2024年度的65.4%提升至2025年的70.9%，主要由于高毛利创新产品的收入占比提升，以及公司持续推动的生产工艺改进、供应链优化等降本措施的有效实施。不断完善的产品布局以及持续的降本增效工作，使公司在面临激烈的市场竞争情况下，仍能保持优质的产品质量及突出盈利能力。公司在业务规模扩大的同时，费用控制效果显著，销售及管理费用率较2024年相比从49.6%降至45.8%。报告期内，公司发生研发费用人民币4076万元，主要用于神经介入医疗器械及脑机接口等创新产品的开发。截至目前，公司已取得以下各项进展：(1)在缺血性卒中领域，公司已取得颅内血栓抽吸导管、取栓支架及配套通路产品的注册证。公司的自膨式颅内药物洗脱支架已完成对照临床试验，注册申请已获NMPA受理。根据公开信息查询结果，目前全球未有类似产品获批上市，公司在此类产品的研发进度上领先业界。在颈动脉狭窄领域，公司正推动开展颈动脉支架的临床试验工作；(2)在出血性卒中领域，公司是获证最全面的国产公司，实现颅内支架（获NMPA创新医疗器械认定）、血流导向装置、栓塞弹簧圈、神经血管封堵球囊导管的完整布局；(3)同时，公司正积极推进创新产品介入式脑机接口的研发工作。该产品在有效提取大脑信号以用于完成人机交互的同时，保障了手术的安全性和产品长期植入的稳定性，有望在2026年开展首例人体临床试验。2025年，公司的海外市场收入较2024年增长101.3%，这主要归功于公司快速推进的海外产品注册工作及产品推广工作。海外市场方面，公司的取栓支架、封堵球囊导管、远端通路导管以及微导管已取得CE或FDA认证，并在其他13个国家或地区取得56项注册证书。截至目前，公司还在其他29个国家或地区开展超过130个产品注册工作，扩展销售管道，为实现海外销售的长期目标建立基础。2025年，公司经营性现金流1.55亿元，账面现金及存款7.86亿元，整体资金状况稳健。依托扎实的财务实力，公司已于2025年完成股份回购3936万港元，并将持续推进股份回购工作，积极维护全体股东利益。此外，公司计划于2026年提交A股科创板上市申请，借助登陆境内资本市场进一步提升股东回报水平与股份市场流动性。  Copyright 2026 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com